Porcelain gallbladder is rare manifestation of chronic cholecystitis. calcification of the gallbladder wall is present between 0.06%-0.8% of cholecystectomy specimens. the pathogenesis is still unknown but it is believed that it caused by irritation the gallbladder by stones which lead to chronic inflammation associated with calcium deposit. calcification of the gallbladder wall is associated w...

Biliary tract cancers are rare but fatal malignancies, with increasing incidence in Shanghai, China. Gallstones, the primary risk factor for biliary tract cancer, typically result from oversaturation of cholesterol in bile. We examined the association of five variants in three lipid metabolism-related genes (CETP, ABCG8 and LRPAP1) and biliary tract cancers and stones in a population-based case...

Gallbladder cancer, the most common of biliary tract cancer, is often diagnosed at an advanced stage with ensuing poor survival rates. Imaging may allow for earlier diagnosis, however there may be significant overlap with nonmalignant conditions of the gallbladder in early stages of cancer. In this pictorial essay, we use various examples to describe the utility of magnetic resonance imaging in...

Carcinoma of the gallbladder is the most frequent tumor of the extrahepatic biliary tract, and the fourth commonest upper gastrointestinal malignancy. Of the histologic types, adenocarcinoma is the most frequent (80%) (1,2). Gallbladder cancer probably has a multifactorial etiology. More than 80% of patients diagnosed with gallbladder cancer have gallstones. Karyotipic abnormalities, such as mu...

Breast cancer is usually associated with metastases to lungs, bones and liver. Breast carcinoma metastasizing to the gallbladder is very rare. We report the case of 45-year-old female with clinical presentation of acute Cholecystitis, who underwent cholecystectomy in emergency. The Gallbladder showed a nodule on the Gallbladder wall. Histological examination disclosed a metastasis from a lobula...

Background/Aims: Few studies have assessed the prognostic value of the primary tumor maximum standardized uptake value (SUVmax) measured by 2-[F]-fluoro-2-deoxy-D-glucose PET-CT for patients with bile duct and gallbladder cancer. Methods: A retrospective analysis of 61 patients with confirmed bile duct and gallbladder cancer who underwent FDG PET-CT in Kangbuk Samsung Medical Center (Seoul, Kor...

Gallbladder cancer is the most common biliary tract malignancy with the worst overall prognosis. CD109 is a co-receptor of TGF-β1 and suppresses TGF-β signaling. In this study, CD109 protein expression in three subtypes of gallbladder cancer was examined by immunohistochemistry on human tissue samples and tissue microarrays. We found that CD109 is specifically expressed in malignant squamous ce...

Gallbladder cancer is the most common malignant tumor of the biliary tract. The majority of cases are adenocarcinoma (AC). Pure squamous cell carcinoma (SCC) of gallbladder accounts only 3% of the malignant neoplasm of this organ. Many patients are at advanced stage when diagnosed and have bad therapeutic efficacy. At present, radical surgery is the only chance to gain long-term survival for pa...

BACKGROUND Gallbladder cancer is sometimes incidentally uncovered following cholecystectomy for gallstones diseases. The supposed highly variable prevalence of incidental gallbladder cancer through our country is unknown. OBJECTIVE To explore the prevalence of incidental gallbladder cancer in our tertiary-care hospital. METHODS A cross-sectional study was carried out on patients who consecu...