The reduced metastability of biliary cholesterol in the gall bladder bile of patients with cholesterol gall stones has been well shown. The purpose of this study was to examine the hypothesis that such a difference in metastability already exists in hepatic bile. Paired hepatic and gall bladder bile samples were collected from 10 patients with cholesterol gall stones and six patients without ga...

BACKGROUND Patients with spinal cord injury (SCI) have an increased prevalence of gallstones. AIMS To study prospectively the incidence of gallstones and gall bladder contractility in patients with SCI. PATIENTS AND METHODS Thirty six consecutive patients with SCI were studied: 18 patients with SCI above thoracic 10 neuronal segment (> T10) and 18 patients with SCI below T10 (< T10). An equ...

The objective in the present study was to explore the histological, histochemical and micrometric changes of developing gall bladder during the fetal life of Gaddi sheep. A total number of 40 Gaddi sheep foetii samples were collected irrespective of sex and without any external anomaly or pathology. The age estimation of each foetus was done and accordingly the foetii were grouped as; group-I (...

Diverse physiological and behavioural mechanisms allow animals to effectively deal with stressors, but chronic activation of the stress axis can have severe consequences. We explored the effects of chronic social stress on agonistic behaviour and gall bladder function, a critical but widely neglected component of stress-induced gastrointestinal dysfunction. Prolonged cohabitation with dominant ...

OBJECTIVE To assess the safety of confining histological examination to gall bladders with radiological and macroscopic features suggestive of cancer. DESIGN Retrospective study. Setting Department of Histopathology, National Hospital of Sri Lanka. METHOD Analysis of all cholecystectomies performed at a tertiary care hospital during a one year period. Computerised histopathological reports ...

Gall bladder cancer is one of five most common malignancies of the gastro-intestinal tract. Most of the cancers are detected during histological examination after cholecystectomy. Females are more commonly affected than males with a ratio of 4:1. A direct association exists between the presence of cholelithiasis and the development of gall bladder carcinoma. In patients with gall bladder carcin...

Our previous study demonstrated that curcumin, an active compound of Curcuma xanthorrhiza and C. domestica, produces a positive cholekinetic effect. A 20 mg amount of curcumin is capable of contracting the gall bladder by up to 29% within an observation time of 2 h. The aim of the current study was to define the dosage of curcumin capable of producing a 50% contraction of the gall bladder, and ...

The gall bladder is least common intra-abdominal organ to be involved by tuberculosis. It is either part of systemic miliary tuberculosis or abdominal tuberculosis. Isolated gall bladder tuberculosis is even rarer, can presents either as calculus or acalculus cholecystitis. Gall bladder tuberculosis presenting as a localized perforation with a sinus formation into anterior abdominal wall is unr...

Gall-bladder emptying in response to a standard meal was assessed in 34 patients with radiolucent gall stones and 34 matched controls. Percentage gall-bladder emptying, derived from volume measurements made on standardised oral cholecystography, was significantly higher at 15 minutes in the patients than the controls (mean +/- SE of mean 38.0 +/- 3.7% v 28.0 +/- 3.8%). This difference was maint...

BACKGROUND Carcinoma of the gall bladder has a guarded prognosis with predominant sites of involvement being liver and regional nodes. Osseous metastasis in carcinoma of the gall bladder is rare and hence bone scintigraphy does not form a part of the routine work-up for such patients. CASE REPORTS We describe two patients with carcinoma of the gall bladder with osteolytic metastasis (stage 4)...