introduction: compounds which are used to treat organophosphate (op) poisoning are not able to fully alleviate long lasting effects. they are mainly used to antagonize cholinergic effects of ops. however, non-cholinergic effects, such as interference with different neurotransmitter systems, especially gaba release and uptake, are recently attracting more attentions. we have tried to investigate...

gamma aminobutyric acid (gaba) is one of the inhibitory neurotransmitters that may have the ability torelieve the intensity of stress. heat stress remains a major threat for duck production in summer in most areas of china. the current study was conducted to investigate the effect of dietary gaba on performanceparameters and plasma metabolites of heat exposed ducks. two thousand cherry valley d...

The ρ 1 GABA receptor cloned from rat retina is down-modulated by protons. sensitivities of human and rat ρ 1 GABA receptors to extracellular pH.

Introduction: Compounds which are used to treat organophosphate (OP) poisoning are not able to fully alleviate long lasting effects. They are mainly used to antagonize cholinergic effects of Ops. However, non-cholinergic effects, such as interference with different neurotransmitter systems, especially GABA release and uptake, are recently attracting more attentions. We have tried to investi...

objective(s) indigofera tinctoria linn. of fabaceae family is claimed to be useful to control epileptic seizures in the indian system of folkore medicine. this study was designed to evaluate i. tinctoria and to verify the claim. materials and methods seizures were induced in male albino rats with pentylenetetrazole (ptz). the test group animals were administered ethanolic extract of indigofera ...

Chilling damage under 15ºC in anthurium cut flowers reduces the vase-life, quality and marketability of the product. In the present experiment, GABA postharvest treatment (0, 1 and 5 mM) was studied on the vase-life, total soluble solid (TSS), H2O2 content, proline content, spathe browning, catalase and superoxide dismutase enzymes activity of Anthurium andraeanum...

     Gamma-aminobutyric acid (GABA) is an important inhibitory transmitter in central nervous system and is involved in pathophysiology of epilepsy. Pentylenete-trazole (PTZ), a convulsant agent, partly acts via anion channel of GABAA receptor. Ivermectin, an antiparasitic agent and a GABAA agonist, has anticonvulsant effect in animal seizure models. Cholestasis increases ...

Objective: GABAergic system is a target for various groups of medications including sedatives, anxiolytics, muscle relaxants, antidepressants and antiepileptics. Several foods or food ingredients are able to affect the by inhibition γ-aminobutyric acid (GABA) degrading enzymes GABA-transaminase succinate semialdehyde dehydrogenase. The purpose this study investigate inhibitory effects tea (Came...