A label-free and enzyme-free three-way G-quadruplex junction sensing system for the amplified detection of 17β-estradiol has been constructed by the ingenious coupling of split G-quadruplex DNAzyme with toehold-mediated strand displacement. The biosensor is ultrasensitive, enabling the visual detection of 17β-estradiol concentrations as low as 1 fM without instrumentation.

Abstract In this paper, a novel super-junction (SJ) MOSFET with enhanced switching performance and ruggedness is proposed investigated by the method of TCAD simulations. An N + /P - polysilicon junction gate electrode separation layer between P-base P-pillar are introduced to trench SJ-MOSFET. For gate, P located in bottom plays role insulating layer, which efficiently reduces charge (Q G ), th...

statement of the problem early detection of periodontal disease and distruction is important for prevention of further destruction of the tissues. we carried out this study to determine the normal cement enamel junction (cej) to alveolar bone crest (abc) distance in the interproximal area of primary molars on bitewing (b. w) radiographs in healthy 7-9 year old girls living in hamadan, iran. mat...

varicose veins are an extremely common medical condition (present in 5-30% of adults). surgery remains the gold standard of care in patients with varicose veins, however several newer interventions have been recently introduced which need to be evaluated. during the standard surgery it is imperative to demonstrate and ligate the tributaries of the saphenofemoral junction in combination with str...

it was thought previously that cardiac muscle gap junctions provide low-resistance connections between cells and permit the local-circuit current to flow. some evidences show that myocardial cells may not require low-resistance connections for successful propagation of the action potential (ap). it seems that some other types of mechanisms must be involved in ap propagation. in this article, we...

Holliday junctions are important structural intermediates in recombination, viral integration, and DNA repair. We present here the single-crystal structure of the inverted repeat sequence d(CCGGTACCGG) as a Holliday junction at the nominal resolution of 2. 1 A. Unlike the previous crystal structures, this DNA junction has B-DNA arms with all standard Watson-Crick base pairs; it therefore repres...

open-channel junctions have a broad application in civil and environmental engineering. formation of a low-pressure zone with recirculating flow (high sedimentation) accompanied by a high-velocity zone (high erosion) is the most characteristic feature of flow in junctions. a large number of researches have been performed to study the complexity of the flow in junctions in open-channel flows. in...

Introduction: In recent dentin adhesive systems etching of enamel/dentin are achieved simultaneously. The objective was to evaluate the microleakage of composite restorations using Single Bond2 (5th generation), Clearfil S3 Bond and G Bond (7th generation). Methods: Class V cavities were prepared on  45 extracted intact premolars with gingival margins at the cementoenamel junction and they were...

In this article, we combine the homophase junction g-C3N4 prepared by recrystallization with small particles of MoS2 treated ball milling through a simple method ultrasonic assisted oil bath, which improves light absorption capacity catalyst and promotes electron transport separation efficiency electrons, photocatalyst capable efficiently degrading pollutants was prepared.

A comprehensive review is presented of single-molecule junction conductance measurements across families of molecules measured while breaking a gold point contact in a solution of molecules with amine end groups. A theoretical framework unifies the picture for the amine-gold link bonding and the tunnel coupling through the junction using density functional theory based calculations. The reprodu...