نتایج جستجو برای: fungal biotransformation

تعداد نتایج: 57641  

2014
Sailendra Goyari Shantibala S Devi Mohan C Kalita Narayan C Talukdar

Forest ecosystem harbour a large number of biotic components where cellulolytic microorganisms participate actively in the biotransformation of dead and decaying organic matter and soil nutrient cycling. This study explores the aerobic culturable cellulolytic microorganisms in the forest soils of North East India. Soil samples rich in dead and decaying organic matter were collected from eight c...

2017
Zuriat Jabbar Hannana Maryam Sana Maqsood Sikander Ali

Steroids are widespread in nature and are important compounds present in living systems. These compounds include different sterols, bile salts and steroid hormones like estrogen, androgens, testosterones etc. and have numerous therapeutic applications. Microbial biotransformation of steroids is one of the applications of microorganisms in the large-scale industries and it also have certain adva...

2015
SYED ADNAN ALI SHAH SADIA SULTAN MUHAMMAD IQBAL CHOUDHARY

Objective: Microbial catalysis is used in the commercial production of many bioactive steroids. Solid phase microbial fermentation of anabolic steroid, dihydrotestosterone (DHT, 1), was carried out with ascomycete fungal strain Fusarium oxysporum (NRRL-1392). Methods: Sabouraud-4% glucose-agar was used to cultivate the fungal cultures as solid phase medium. Substrate 1 was incubated with Fusari...

2016
Ander Achotegui-Castells Gianni Della Rocca Joan Llusià Roberto Danti Sara Barberini Mabrouk Bouneb Sauro Simoni Marco Michelozzi Josep Peñuelas

The canker-causing fungus Seiridium cardinale is the major threat to Cupressus sempervirens worldwide. We investigated the production of terpenes by canker-resistant and susceptible cypresses inoculated with S. cardinale, the effect of these terpenes on fungal growth, and the defensive biotransformation of the terpenes conducted by the fungus. All infected trees produced de novo terpenes and st...

Journal: :Molecular ecology 2009
E Magnanou J R Malenke M D Dearing

The ability of herbivores to switch diets is thought to be governed by biotransformation enzymes. To identify potential biotransformation enzymes, we conducted a large-scale study on the expression of biotransformation enzymes in herbivorous woodrats (Neotoma lepida). We compared gene expression in a woodrat population from the Great Basin that feeds on the ancestral diet of juniper to one from...

Journal: :The Journal of antibiotics 1996
M Kuhnt F Bitsch J France H Hofmann J J Sanglier R Traber

In order to mimic the human metabolic pathway of cyclosporin A (CyA) a total of 28 bacterial and 72 fungal strains was screened for their ability to transform CyA. Among 3 bacteria and 11 fungi, which produced the main human metabolite OL-17 [eta HyMeBmt1]CyA, Actinoplanes sp. (ATCC 53771) achieved the best transformation rate (5.4%). Furthermore, the two N-demethylated minor products [Leu4]CyA...

Journal: :Catalysts 2022

5-hydroxymethylfurfural (HMF) is a platform chemical that can be converted into wide range of high-value derivatives. Industrially, HMF-based derivatives are synthesized via catalysis. However, biocatalytic transformation has emerged as an attractive alternative. Significant advances have been made in the last years using isolated enzymes and whole-cell biocatalysts HMF biotransformation. Nonet...

2014
Ciddi Veeresham

Microbial transformation is a complementary tool in the investigation of drug metabolism. In the present investigation, biotransformation of vincamine was studied using microbial cultures. Bacterial, fungal, and yeast cultures were employed to elucidate the metabolism of vincamine. The results indicate that a number of microorganisms metabolized vincamine to various levels to yield three major ...

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