Fulminant hepatic failure is a serious disease with significant mortality and morbidity. Identifying the cause of fulminant hepatic failure in managing these patients and predicting the outcome. Drug induced liver injury is a common but challenging entity. New medications and drugs with recently discovered hepatotoxicity require the clinician’s careful attention. Quetiapine is an antipsychotic ...

A new type of activated charcoal for the direct hemoperfusion (DHP) has been developed for use in treatment of fulminant hepatic failure. Bead-type activated charcoal from petroleum pitch (BAC) was coated with polyetherurethane. The coating has permitted the charcoal to minimize the number of released microparticles and yet to show nearly the same adsorption performance as that of the non-coate...

Serological markers for hepatitis B virus infection have been examined in 34 patients with acute hepatitis B, 17 of whom developed fulminant hepatic failure. Hepatitis B surface antigen concentrations were significantly lower and hepatitis Be antigen was less frequently detectable in patients with fulminant hepatic failure compared with those with acute hepatitis (median 0.64 micrograms, range ...

Fulminant hepatic failure is a fatal complication of iron intoxication. Currently, there no well-established treatment. A 23-year-old Japanese woman, with past medical history deficiency anemia, presented fulminant caused by Multiple organ progressed despite plasma exchanges and deferoxamine therapy, she subsequently developed acute respiratory distress syndrome. Even though Venous-Venous Extra...

Fulminant hepatitis is an uncommon complication of herpes simplex virus infection. Patients at risk, in particular pregnant women and immunosuppressed patients presenting with fulminant liver failure, receiving delayed acyclovir intervention may lose significant liver parenchyma prompting the need for liver transplantation. The diagnosis is often not straight forward due to the lack of specific...

Cerebral injury may persist and brain death may occur following an emergency liver transplantation (LT) for fulminant hepatic failure (FHF) even if the graft functions well. We herein present two patients developing brain death following emergency LT for FHF. How to cite this article Akoglu M, Sürmelioglu A, Ozer I, Ercan M, Ulas M, Akdogan M, Bostanci EB. Brain Death after Liver Transplantat...

Thirteen out of 17 patients with fulminant hepatic failure had plasma fibronectin concentrations below the normal range (194--472 micrograms/ml), the mean concentration in all 17 patients being 117.9 +/- SE 19.4 micrograms/ml. There was a significant negative correlation between plasma fibronectin concentration and aspartate aminotransferase activity, suggesting that fibronectin is consumed dur...

Following an elective transphenoidal resection of a pituitary tumor, a 66-year-old Hispanic male acutely developed fulminant hepatic failure and severe coagulopathy. He received parenteral corticosteroids the day prior to surgery, and was first noted to have significant coagulopathy intraoperatively. Despite aggressive workup and treatment for fulminant hepatic failure, the patient developed mu...

Although the incidence of fulminant hepatic failure appears to have decreased worldwide, the management of this dreaded condition remains unsatisfactory (1). Despite ingenious methods of treatment, the mortality in patients with grade IV coma is still between 80 and 90% in most major series (15, 20). Furthermore the mortality is nearly 100% in patients ov~r the age of 45 who develop grade IV co...