BACKGROUND Fructose malabsorption is characterized by the inability to absorb fructose efficiently. As a consequence fructose reaches the colon where it is broken down by bacteria to short fatty acids, CO2, H2, CH4 and lactic acid. Bloating, cramps, osmotic diarrhea and other symptoms of irritable bowel syndrome are the consequence and can be seen in about 50% of fructose malabsorbers. Recently...

UNLABELLED Fructose malabsorption has not been well-defined in Thai populations but there has been increasing consumption of fructose-fortified drinks. OBJECTIVES To assess the incidence of fructose malabsorption and intolerance in Thai normal subjects as well as the facilitating effect of glucose on fructose absorption. METHODS Twenty-five gram of fructose was ingested by 77 subjects (37 m...

Fructose Likely Does Have a Role in Hypertension To the Editor: Ha et al recently performed a meta-analysis and concluded that fructose intake is unlikely to have a role in hypertension. This conclusion is unjustified. Less than half of the studies were randomly assigned, and blood pressure (BP) was the primary outcome in only 3 of 15 studies. BP measurements were not postprandial, at which tim...

Fructose and mannitol are fermented by Clostridium thermocellum in a medium containing salts and 0.5% yeast extract. The initial reaction in the catabolism of fructose was found to be the formation of fructose l-phosphate by phosphoenolpyruvate (PEP):fructose phosphotransferase which resembles the Kundig-Roseman phosphotransferase system. The phosphorylation of fructose l-phosphate to form fruc...

Sustained fructose consumption has been shown to induce insulin resistance and glucose intolerance, in part, by promoting oxidative stress. Alpha-lipoic acid (LA) is an antioxidant with insulin-sensitizing activity. The effect of sustained fructose consumption (20% of energy) on the development of T2DM and the effects of daily LA supplementation in fructose-fed University of California, Davis-T...

The elucidation of enzyme systems involved in the metabolism of fructose has done much in clarifying its metabolic pathway. Recent work (1, 2) on glucose and fructose metabolism by normal and diabetic rat livers has suggested that fructose can be metabolized by liver enzyme systems that are independent of glucose metabolism. Similar enzyme systems that act upon fructose have been reported to oc...

Objective: The aim of this study was to investigate the effect of pre-treatment with curcumin on metabolic changes induced by two different pathophysiological mechanisms in rats (fructose diet and streptozotocin (STZ)-induced diabetes mellitus). Materials and Methods: Five groups with 10 rats per group were investigated: control group (healthy rats), fructose diet groups without any pre-treatme...

Glucose (32 mM) and fructose (36mM) of cucumber juice were degraded simultaneously by Lactobacillus plantarum, but at different rates and extents. Glucose depletion was slightly more rapid than fructose during the exponential growth phase, but slower thereafter and stopped before exhaustion. In contrast, fructose degradation continued until all naturally present fructose was exhausted. When cuc...