BACKGROUND The most common complication of IVF is multiple pregnancy, which occurs in 25% of pregnancies following the transfer of two embryos. Single embryo transfer can minimize twin pregnancies but could also lower live birth rates. Our aim was to perform a systematic review of randomized trials to determine the effectiveness of single versus double embryo transfer. METHODS Cochrane Collab...

Sir, We read with great interest the study entitled ‘Transfer of fresh or frozen embryos: a randomized controlled trial’ (Wong et al., 2021), recently accepted for publication in Human Reproduction. In this well-designed (n = 204), Wong al. tried to address question whether elective ‘embryo freeze-all strategy’ (i.e. transfer frozen-thawed blastocysts [FETs]) was superior ‘conventional and FETs...

BACKGROUND Frozen embryo transfers are characterized by impaired pregnancy outcome and increased incidence of pregnancy loss as compared with fresh IVF/ICSI embryo transfers. In this study, we performed a retrospective analysis of clinical and embryological factors that potentially influence the outcome of frozen embryo transfer. METHODS We reviewed the outcome of 1242 frozen embryo transfers...

INTRODUCTION In several clinics, elective single-embryo transfer (eSET) is applied in a selected group of patients based on age and the availability of a good-quality embryo. Whether or not eSET can be applied irrespective of the presence of a good-quality embryo in the first cycle, to further reduce the twin pregnancy rate, remains to be elucidated. METHODS In patients <38 years two transfer...

OBJECTIVE To describe a case of monozygotic triplet pregnancy following egg donation and the transfer of a single frozen-thawed embryo. DESIGN Case report. SETTING District general hospital and regional department of fetal medicine in northeast England. PATIENT(S) A 38-year-old woman with a 2-year history of primary infertility due to severe endometriosis and poor ovarian reserve who conc...

background: sildenafil citrate may increase endometrial thickness and affect the outcome of frozen-thawed embryo transfer cycles. objective: the aim of this study was to estimate the effect of sildenafil citrate on ultrasonographic endometrial thickness and pattern and to investigate the estrogen level on the day of progesterone administration, the implantation rate and chemical pregnancy rate ...

Background Infertility as one of most concerning topics in childbearing age mothers needs better managements with less complications and IVF can be assumed as an efficient method. This study aimed to compare pregnancy outcomes in fresh and frozen embryos transferred in IVF cycles. Methods In a retrospective study, 11201 patients underwent IVF cycles from 21st March 2013 to 20th March 2014 and...

BACKGROUND GnRH agonist and antagonist were developed to control the premature release of LH surge. There is some difference between two protocols. OBJECTIVE We compared the outcome of frozen-thawed embryo transfer in infertile women who used GnRH agonist or antagonist protocol for previous COH cycle and evaluation of any adverse effect of GnRH antagonist on oocyte and embryo. MATERIALS AND...