Antihypertensive drugs undergo first-pass metabolism and therefore have low oral bioavailability. It causes an increase in the frequency of drug use concentration fluctuations that affect patient comfort. The sustained release tablet formulation was chosen because it can deliver active substance with good An antihypertensive be used is celery extract contains flavonoids, so a made using xanthan...

The present work was aimed at formulation development, evaluation and comparative study of the effects of superdisintegrants in Cefixime 50 mg oral disintegrating tablets. The superdisintegrants used for the present study were sodium starch glycolate and crosscarmellose sodium. The formulated tablets were evaluated for various tableting properties, like hardness, thickness, friability, weight v...

6.1 Literature review matrix Taha E. et al (2015) evaluated Diclofenac Sodium (DS) matrix tablets prepared by direct compression method under different compression forces using ethyl cellulose as matrix forming material. The produced tablets were characterized for hardness, friability, drug content, weight variations and in vitro drug release. Incompatibility study carried out using DSC FT-IR s...

The aim of the present study was to develop a sustained release monolithic system for the low solubile/low dose glipizide, for the treatment of type II diabetes mellitus. The matrices were prepared by dry blending of polymers hydroxy propyl methyl cellulose (HPMC) or erodible Eudragit (ammonio methacrylate copolymers) and other excipients using direct compression method and were characterized u...

Cinnamon bark (Cinnamomum burmannii) is used traditionally and has an ingredient containing cinnamic acid compounds. Colocasia esculenta (L) Schott leaves contains of flavonoids, alkaloids, tannins, saponins, steroids, terpenoids. Both the plants C. burmannii have potential as anti-diabetics because they can lower blood glucose levels. This study aims to make combination tablets extract with va...

The purpose of this research is to capitalise on the potential non-traditional plant species in Republic Moldova from families Asteraceae (cup Silphium perfoliatum; cardoon Cynara cardunculus), Fabaceae (fodder galega Galega orientalis, sand sainfoin Onobrychis arenaria), Hydrophylaceae (phacelia Phacelia tanacetifolia), Malvaceae (curly mallow Malva crispa; Virginia Sida hermaphrodita) and Poa...

Maize (Zea mays L.) is widely cultivated worldwide for food, feed, and fuel uses. forage has become a valuable feed material, there much interest in characterizing its friability, as friability may shape value through effect on ingestibility. The objective of this study was to characterize the maize based milling behavior within collection inbred lines maize. We proposed two indexes—Particle Si...