A melanotic macule is a benign pigmented lesion of oral cavity characterised by increase in melanin pigmentation. Presented here is a case report of 12 year old girl with black pigmented area on right buccal mucosa. An excision biopsy was done which confirmed the diagnosis by as melanotic macule.

Lentigo maligna (LM) is an in situ form of melanoma which can progress into invasive lentigo maligna melanoma (LMM). Variations in the pigmentation and thus visibility of the tumour make assessment of lesion borders challenging. We tested hyperspectral imaging system (HIS) in in vivo preoperative delineation of LM and LMM margins. We compared lesion margins delineated by HIS with those estimate...

1181 Dermoscopy of Pigmented Lesions of the Mucosa and the Mucocutaneous Junction: Results of a Multicenter Study by the International Dermoscopy Society (IDS) Andreas Blum, MD; Olga Simionescu, MD; Giuseppe Argenziano, MD; Ralph Braun, MD; Horacio Cabo, MD; Astrid Eichhorn, MD; Herbert Kirchesch, MD; Josep Malvehy, MD; Ashfaq A. Marghoob, MD; Susana Puig, MD; Fezal Özdemir, MD; Wilhelm Stolz, ...

Topical imiquimod cream is increasingly applied in the treatment of lentigo maligna (LM), in particular for large lesions where surgery may lead to disfiguring scars. Published studies suggest that more frequent and prolonged treatment with topical imiquimod is associated with higher efficacy. In this study we prospectively treated 27 patients suffering from LM on the face with imiquimod 5% cre...

Dermatology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA *Author for correspondence: [email protected] SUMMARY Lentigo maligna and lentigo maligna melanomas present diagnostic and treatment dilemmas due to their frequent presence within a background of sun-damaged skin, and their location o...

Imiquimod activates the immune system when applied to a local area. We report a patient with a history of well-controlled myasthenia gravis who was prescribed imiquimod for lentigo maligna. Treatment was halted after 2 weeks when the patient reported itching and irritating sensations in his throat, consistent with previous myasthenia exacerbations. The symptoms improved once imiquimod use was d...