Fragment C of tetanus toxin appears to retain most of the determinants of the tetanus toxin molecule insofar as interactions with neural or thyroid membranes and with gangliosides are concerned. Thus, unlabeled fragment C is nearly as effective as unlabeled tetanus toxin in inhibiting the binding of either ‘251-labeled toxin or ‘251-labeled thyrotropin to neural or thyroid membranes. ‘251-label...

One conjecture is proposed on the text of Varro’s Bellum Sequanicum (23 B = 106 H 1 C), dulci … sapore for dulcis saporis, and a handful variant readings are reconsidered in fragment Chorographia (13 112 17 C 16 M).

We have found the in vivo-regulated nirB promoter (PnirB) to be effective for directing expression of a number of antigens in salmonella in vivo. We wished to determine if other in vivo-regulated promoters have utility for antigen expression in salmonella and to compare the effectiveness of these promoters with that of PnirB. To this end, we have devised a scheme that allows the promoter elemen...

The fall armyworm (FAW), Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is an invasive insect pest of India native to the Western Hemisphere. damages more than 350 plant species. FAW genetically divided into two strains viz. corn (C) strain which feeds mostly on maize, sorghum, etc. and other a rice (R) that prefers small grasses. In present study, samples were collected from crop...

The aim of this work was to obtain the recombinant single chain variable fragments of antibodies (scFv) against human protein C, the key component of blood anticoagulation system. For this purpose a peptide that mimics a Pro144-Leu155 sequence of protein C was synthesized and the murine immune scFv library against this peptide was constructed. The protein C specific scFv 9E were selected from t...

TLR signaling is essential to innate immunity against microbial invaders and must be tightly controlled. We have previously shown that TLR9 undergoes proteolytic cleavage processing by lysosomal proteases to generate two distinct fragments. The C-terminal cleavage product plays a critical role in activating TLR9 signaling; however, the precise role of the N-terminal fragment, which remains in l...

Abstract: Background: Hemiscorpius lepturus is a medically important scorpion found along the Iranian borders, especially near to Khuzestan Province in the south-west of Iran. This is the only non-buthid scorpion which is potentially lethal in southern Iran and is responsible for severe dermonecrotic scorpionism. OBJECTIVES: In this study, DNA fragment of the mitochondrial cytochrome c oxidase ...