The present study evaluated the in vitro efficacy of ciprofloxacin (CPFX) in combination with gentamicin (GM) using agar dilution checkerboard method against six blood culture isolates of Salmonella enterica serovar Typhi with CPFX minimum inhibitory concentration (MIC) values of 0.75 - 1.25 microg/ml and GM MIC values of 0.75 - 2 microg/ml. When used in combination, the fractional inhibitory c...

Objective(s): To evaluate the in vitro interaction between different extracts of Thymbra spicata L. and certain antimicrobial drugs of different mechanisms, including ampicillin, cefotaxime, amikacin and ciprofloxacin. This study was performed against multidrug-resistant strains of Staphylococcus aureus and Klebsiella pneumoniae. Materials and Methods: Evaluation of antibacterial activity and ...

Natural products with antimycobacterial adjuvant potential may be utilized to address the rise of multidrug-resistant tuberculosis (TB). The antioxidant-rich oil palm (Elaeis guineensis) fruit (OPF) was investigated for activity against Mycobacterium (MTB) H37Ra using bio-guided fractionation techniques, followed by determination fractional inhibition index (FIC) first-line anti-TB drugs. In vi...

Listeria monocytogenes is one of the major causes of infections in developing countries. In this study, chemical composition and anti-listerial effect of the essential oil of Zataria multiflora Boiss. alone and in combination with monolaurin were evaluated at different pH values (5, 6, and 7) and temperatures (5 ˚C and 30 ˚C). Chemical composition of Zataria multiflora Boiss. essential oil was ...

The inhibitory activity of a semipure fraction from the plant, Acalypha wilkesiana assigned as 9EA-FC-B, alone and in combination with ampicillin, was studied against methicillin-resistant Staphylococcus aureus (MRSA). In addition, effects of the combination treatment on PBP2a expression were investigated. Microdilution assay was used to determine the minimal inhibitory concentrations (MIC). Sy...

The anti-Listeria monocytogenes activity of four essential oils (EOs) (Salvia officinalis, Citrus limon, Mentha piperita and Thymus vulgaris) bacteriocin bacLP17, added alone or in mixture active edible coatings, was determined artificially contaminated shrimps. minimal inhibitory concentration (MIC) values the EOs were against NCTC 10888 strain L. by using broth microdilution method. checkerbo...

INTRODUCTION Acute respiratory infections (ARI) contribute to more than 75% of health care seeking in primary health care facilities in India. Respiratory tract infections (RTIs) are managed frequently by β-lactam, macrolide and fluroquinolone class of antibiotics. However, these recommended classes of antibiotic have shown resistance in community settings. Antibiotic combinations may provide b...

Background: The increasing demand for natural preservatives results in their extended usefulness. The objective of the present study was to investigate the physicochemical and antioxidative characteristics of Rhus coriaria L. (sumac) fruit and comparison of its antioxidative and antibacterial activity with Zataria multiflora Essential Oil (ZEO) as native Iranian natural additives. Methods: Ant...

The appearance of antifungal resistance promotes the investigation therapeutic options. There are few studies on combined effect drugs and essential oils (EOs). In present work, regarding association eight EOs Andean plants with agents against a panel fungi strains. Combinatorial effects were determined using Fractional Inhibitory Concentration Index (FICI) Dose Reduction (DRI). A combination A...