BACKGROUND Topical photodynamic therapy (PDT) has been increasingly used to treat malignant skin tumors including the Bowen disease. However, patients could be displeased with the long incubation time required for conventional PDT. OBJECTIVE We evaluated the efficacy and safety of PDT with a short incubation time of ablative CO2 fractional laser pretreatment for treating Bowen disease. METH...

OBJECTIVES Breast cancer is one of the most common malignancies in women. Hormonal treatment and chemotherapy induce a transient or permanent menopause status. Vulvovaginal atrophy (VVA) is a frequent debilitating symptom of menopause that is best treated with local or systemic estrogen formulations. Because estrogens drive the growth of the majority of breast cancers, most effective VVA therap...

BACKGROUND CO2 laser has not only become the most widely used laser in dermatological surgical practice, but it has also proved to be highly effective in treating aesthetic imperfections. OBJECTIVE To examine the efficacy and safety of a novel fractional CO2 laser combined with a radiofrequency device in different dermatological, surgical and aesthetic fields. METHODS A total of 79 patients...

conclusions despite the healing effects of aeo in burn wounds, petrolatum was more effective than aeo in post-laser wound. results our study indicated higher epithelial confluence and general wound appearance scores (p = 0.045 for both) and less erythema and edema on fifth day in petrolatum (p = 0.009 and p = 0.034, respectively). the results showed less crusting and erythema (p = 0.016 and p =...

BACKGROUND To evaluate the efficacy of fractional carbon dioxide (CO2) laser combined with luliconazole 1% cream for the treatment of onychomycosis and to compare it with that of fractional CO2 laser alone. METHODS This was a randomized, parallel group, 2-arm, positive-controlled, single-center, superiority trial with a 1:2 allocation ratio. Sixty patients with clinical and mycological diagno...

Reports on the use of fractional CO2 lasers to improve skin dyschromia, rhytides, and textural irregularities have increased. However, there is little mention of their impact on patients with traumatic or postoperative scars. Most reconstructive surgical interventions, such as conventional laser resurfacing and mechanical dermabrasion, focus on timing with respect to the return of tissue mechan...

Introdução: The increase in the demand for cosmetic procedures has in turn stimulated the search for effective and safe analgesia.Topical anesthetics are an alternative to infiltrative anesthesia, and promote an appropriate analgesia without inducing adverse effects. Objective: To compare the pain ratings of two topical lidocaine formulations in patients undergoing fractional CO2 laser therapy....

Vitiligo is a common disease with a prevalence of about 0.5-1% for the general population. In many patients disease is resistant despite well-delineated and updated guidelines [1] on implementation methods for the many conventional and novel treatments. Various laser and light treatments, alone or combined have been shown to be effective but are available in only a few centers and require multi...

BACKGROUND Onychomycosis is a fungal infection of the nails caused in most cases by dermatophytes Trichophyton rubrum and Trichophyton mentagrophytes. Despite numerous available antifungal drugs for therapy of this infection, the cure rate is low, with high rates of relapse after treatment and side effects. OBJECTIVES To present a new option for the treatment of onychomycosis, in search of a ...