thimerosal, which is approximately 50% mercury by weight is a preservative widely used in vaccines since the 1930’s. it meets the requirements for a preservative as set forth by pharmacopeia challenge test and has been shown to be effective against a broad spectrum of pathogens. in july 1999, the public health service agencies and vaccine manufacturers agreed that thimerosal should be reduced o...

the purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of glaucoma. following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. the polymers investigated in this study included cellulose derivatives (hec, cmc, ec) and carbopol971p. mann...

objective(s): the purpose of the present study was to prepare and to evaluate a novel niosome as transdermal drug delivery system for propranolol hydrochloride and to compare the in vitro efficiency of niosome by either thin film hydration or hand shaking method. materials and methods: niosomes were prepared by thin film hydration (tfh) or hand shaking (hs) method. propranolol niosomes were pre...

The hydroalcoholic extracts of dried ligulate florets of Calendula officinalis L., dried leaves of Plantago major L., and dried aerial parts of Vinca major L. were prepared and used as the main active ingredients of two types of anti-anorectal disease ointments and suppositories. Benzocaine was used in one of the formulations, while a mixture of belladonna dry extract and ephedrine sulfate ...

conclusions it was shown that combination of pectin and eudragits can relatively control drug release in the upper gi. on the other hand, pectin degraded in the presence of pectinase and formulations were susceptible to the colonic media. results it was shown that in the presence of pectin, formulations without erl had a relative resistance to drug release in sgf. pellets containing pectin and ...

Abstract Kermanshah is a city in west of Iran with a specific customs and cultures between the Kermanshah is a city in west of Iran with a specific customs and cultures between the people who are living here. According to historical documents these cultures are very ancient and belong to more than one thousand years. The climate condition in this place forces people to find the solution of thei...