Solid Lipid Nanoparticles (SLN) have been prepared by high-pressure homogenization and optimized in order to protect ferulic acid from Ferula assa-foetida L. extract. The influence of lipid surfactant concentration on the mean particle size (Z-Ave), polydispersity index (PDI), zeta potential (ZP) SLN was analyzed. In addition, other parameters for preparation acid-loaded nanoparticles, such as ...

OBJECTIVE Ferula assa-foetida, a native species in Iran, is used for treatment of several diseases particularly for neurological disorders in Iranian Traditional Medicine. The aim of this study is to investigate the effect of methanolic roots, fruits, and aerial parts extracts of Ferula assa-foetida on withdrawal syndrome in morphine-dependent mice. MATERIALS AND METHODS Aerial parts, roots, ...

Amorfrutins are isoprenoid-substituted benzoic acid derivatives, which were found in Amorpha fruticosa L. (bastard indigo) and in Glycyrrhiza foetida Desf. (licorice). Recently, amorfrutins were shown to be selective activators of the nuclear receptor PPARγ. Here, we investigated the effects and PPARγ-based mechanisms of reducing inflammation in colon cells by treatment with amorfrutins. In TNF...

Holophaga foetida Liesack et al. 1995 is a member of the phylum Acidobacteria and is of interest for its ability to anaerobically degrade aromatic compounds and for its production of volatile sulfur compounds through a unique pathway. The genome of H. foetida strain TMBS4 T is the first to be sequenced for a representative of the class Holophagae. Here we describe the features of this organism,...

RESUMO A Ilha de São Luís, Estado do Maranhão, configura-se como uma região ecotonal, um misto floresta úmida, mata-de-cocais, vegetação dunas, restingas e manguezais. Diferentemente interior suas zonas costeiras possuem lacuna sobre o conhecimento da família Passifloraceae. Aqui, por meio expedições campo consulta a herbários, nós fornecemos tratamento taxonômico, chave identificação comentári...

INTRODUCTION Considering the prevalence of epilepsy and the failure of available treatments for many epileptic patients, finding more effective drugs in the treatment of epilepsy seems necessary. Oxidative stress has a special role in the pathogenesis of epileptic syndrome. Therefore, in the present study, we have examined the anti-epileptic and anti-oxidant properties of the Ferula Assa Foetid...

Asafoetida (Ferula assa-foetida L.) is one of the endemic medicinal plants in Iran. Analysis karyomorphology and 2Cx DNA measurements (monoploid genome size) 18 Iranian Ferula populations were performed. The vitro embryo-derived root tips examined for karyological studies, via technique squash stain with 2% (w/v) aceto-orcein. Seeds samples leaves Solanum lycopersicum as standard reference (2C ...