Objective: This paper aims to explore the trend, extent and impacting factors of the change in the psychological status of women before and after hysterectomy. Methods: A prospective study was performed to investigate the psychological statuses of 98 female subjects who underwent hysterectomy upon admission and three months after the hysterectomy. Results: The self-rating of the psychological s...

OBJECTIVE To investigate the prevalence, clinical manifestations, and clinical correlates of insomnia in a large cohort of Korean patients with depressive disorders. METHODS We recruited 944 patients with depressive disorders from the Clinical Research Center for Depression of South Korea (CRESCEND) study. Psychometric scales were used to assess depression (HAMD), anxiety (HAMA), psychotic sy...

OBJECTIVE The aim of this study was to validate the psychotic depression assessment scale (PDAS), which includes the six-item melancholia subscale from the Hamilton depression rating scale (HAMD-6) and the five-item psychosis subscale from the brief psychiatric rating scale (BPRS-5). Data from the Clinical Research Center for Depression (CRESCEND) study, which is a 52-week naturalistic trial, w...

BACKGROUND Those injured in accidents commonly have strong emotional reactions to their situation. However, despite the large number of patients who are admitted to general hospitals each year for orthopedic injuries due to an accident, research focusing on psychological disorders due to these injuries is lacking. OBJECTIVE To investigate the presentation and factors related to depression and...

Aims The aim of the study was to investigate potential association between gambling disorder and symptoms sleep problems including insomnia hypersomnolence. Gambling is a behavioural addiction featuring persistent, recurrent resulting in distress impairment function. Lifetime prevalence estimated at 0.6–0.9%, though high quality data UK are lacking. Psychiatric comorbidity common; as physical h...

BACKGROUND Goals of treating major depressive disorder (MDD) include achieving remission and avoiding relapse. It is possible that patients may have a broader view of remission than what is captured via clinician-rated scales. This patient perspective may, in turn, have an impact on treatment outcomes. METHODS The association between a broader conceptualization of remission, based on the Remi...

INTRODUCTION The aim of this study was to compare the concentration of serum Brain-derived neurotrophic factor (BDNF) in patients suffering from major depressive disorder (MDD) considering the severity of MDD episode defined by the Hamilton rating scale for depression (HAMD-17). The other aim was to research the connection between serum BDNF and the symptomatic dimensions of MDD. SUBJECTS AND...

PURPOSE The impact of personality disorders on the treatment of and recovery from depression is still a controversial topic. The aim of this paper is to provide more information on what has led to this disagreement. MATERIALS AND METHODS Clinician-rated Hamilton Depression Rating Scale (HAMD) scores were assessed among 82 depressed outpatients who were receiving a routine treatment combinatio...

Introduction: Depression can present with several symptoms, such as loss of pleasure, feelings guilt, low selfesteem, and disturbed sleep or appetite. In recent socio- economic scenario incidence & prevalence depressionis on increasing trend. SSRIs are the mainstay treatment depression.Objective: anti-inflammatory role escitalopram in freshly diagnosed depression case also to find anycorrel...