OBJECTIVE Fibromyalgia (FMS) is characterized by chronic pain, high psychiatric comorbidity, and the absence of observable pathology. Our objective was to examine positive and negative affective indices, both at the trait and contextual levels, in FMS compared with a chronic pain control group, osteoarthritis (OA). METHODS The sample consisted of 126 female FMS (87) and OA (39) patients from ...

OBJECTIVE Fibromyalgia syndrome (FMS) is a pain syndrome in which common pain in muscle-skeletal system, sleeping disorder and fatigue symptoms coexist. The aim of the present study was to determine SOD and GPX enzyme levels in FMS as well as to investigate possible associations between FMS and Ala9Val polymorphism of MnSOD2 and Pro198Leu polymorphism of GPX1. PATIENTS AND METHODS The study i...

BACKGROUND Fibromyalgia syndrome (FMS) is a chronic condition characterized by widespread pain and associated symptoms. We investigated cerebral activation in FMS patients by functional near-infrared spectroscopy (fNIRS). METHODS Two stimulation paradigms were applied: a) painful pressure stimulation at the dorsal forearm; b) verbal fluency test (VFT). We prospectively recruited 25 FMS patien...

Fibromyalgia (FMS) is a chronic pain syndrome with a complex but poorly understood pathogenesis affecting approximately 10 million adults in the United States. The lack of a clear etiology of FMS has limited the effective diagnosis and treatment of this debilitating condition. The objective of this secondary data analysis was to examine plasma cytokine levels in women with FMS using the Bio-Ple...

The c-fms protooncogene product was identified as the CSF-1 or M-CSF receptor, a polypeptide growth factor that plays a major role in myelomonocytic differentiation. This led us to look for expression of c-fms in fresh acute myeloid leukemia (AML) cells, using Northern blot analysis. c-fms expression was found in the leukemic cells of 28 AML patients, regardless of their stage of differentiatio...

As reported previously, FMS* has been synthesized as a coenzyme analogue1 ) and has been found to inhibit D-amino acid oxidase in competition with FAD2)3 )4). On the other hand, it has been observed that FMS has an inhibitory action on the growth of riboflavin requiring bacteria5). From these results, it was supposed that FMS, as an antivitamin B2, disturbs the metabolic pattern in higher anima...

Fibromyalgia syndrome (FMS) is a complex chronic condition causing widespread pain and variety of other symptoms. It produces pain in the soft tissues located around joints throughout the body. FMS has unknown etiology and its pathophysiology is not fully understood. However, abnormality in circadian rhythm of hormonal profiles and cytokines has been observed in this disorder. Moreover, there a...

Objective: Fibromyalgia (FMS) is characterized by chronic pain, high psychiatric comorbidity, and the absence of observable pathology. Our objective was to examine positive and negative affective indices, both at the trait and contextual levels, in FMS compared to a chronic pain control group, osteoarthritis (OA). Methods: The sample consisted of 126 female FMS (87) and OA (39) patients from th...

OBJECTIVES Fibromyalgia syndrome (FMS) is characterized by complaints of chronic musculoskeletal pain, fatigue, and difficulty in falling asleep. Obstructive sleep apnea syndrome (OSAS) is associated with symptoms, such as morning fatigueness and unrefreshing sleep. We aimed to investigate the presence of OSAS and objectively demonstrate changes in sleep pattern in patients with FMS. MATERIAL...