CASE REPORT The case is presented of a severe Intraoperative Floppy Iris Syndrome (IFIS) in a patient that had been treated with duloxetine. DISCUSSION Tamsulosin is the main etiological agent involved in IFIS. However several cases of IFIS, supposedly secondary to drugs of different groups have recently been reported in the literature. The authors use this case report as a means to discuss w...

With up to 6% of cataract surgeries complicated by vitreous loss,1 anterior vitrectomy is an essential skill of today’s cataract surgeon. Although the incidence of this complication is predictably higher in patients with complex cataracts due to pseudoexfoliation, intraoperative floppy iris syndrome, or posterior polar or dense cataracts, vitreous loss can occur unexpectedly in any case. To dec...

E yes with small pupils present a challenge to cataract surgeons. A pupil that fails to dilate can obscure visualization during all stages of phacoemulsification, making surgery more difficult and increasing the incidence of complications such as nucleus drop, vitreous prolapse, and iris tear. Inadequate pupil dilation is often seen in patients with a history of use of miotic agents, chronic uv...

PURPOSE To extend upon previous reports, observations, and discussions of intraoperative floppy iris syndrome (IFIS) with the goal of providing new insight into the syndrome's pathophysiology, prevention, and treatment. METHODS Following a review of IFIS and its relationship to autonomic pharmacology, evidence for anatomic changes following exposure of humans and other animals to autonomic dr...

Atropine has been used in medical practice for decades and is one of the essential emergency drugs. Its applications ophthalmology have also followed a long trajectory. Therefore, this review intended to explore various uses ophthalmology. strict ophthalmic indications extensive diagnostic therapeutic outlay including Examination under anesthesia, cycloplegic refraction, myopia, amblyopic manag...

The Pentacam’s new densitometry software is not without limitations. A poorly dilated pupil interferes with the device’s sampling technology, and so eyes with pseudoexfoliation, trauma, and intraoperative floppy iris syndrome, for example, are problematic. Also, white cataracts block the system’s ability to sample the central nucleus. Nevertheless, comparison studies with the LOCS III system ha...

1. Chang DF, Campbell JR. Intraoperative floppy iris syndrome associated with tamulosin. J Cataract Refract Surg 2005; 31:664–673 2. Slack JW, Edelhauser HF, Helenek MJ. A bisulfite-free intraocular epinephrine solution. Am J Ophthalmol 1990; 110:77–82 3. Gonnering R, Edelhauser HF, van Horn DL, Durant W. The pH tolerance of rabbit and human corneal endothelium. Invest Ophthalmol Vis Sci 1979; ...