Hepatolenticular degeneration (Wilson's disease) is a rare condition characterised by a defect in biliary excretion of copper resulting in excessive copper accumulation and toxicity. To the most frequent symptoms of this disorder belong liver, neurological or psychiatric disturbances, although other less common clinical features may sometimes be present. Since the clinical presentation of the d...

Wilson disease (WD) is one of the few curable movement disorders that manifests with varied presentations so that WD needs to be considered in any patient with a movement disorder under the age of 50 years. Although WD is one of the causes of myoclonus, it is rarely seen in WD and usually as an associated finding. We report a case of an adolescent female patient of WD who presented with cortica...

This paper continues the study, initiated by Cole and Fleischer in [Cole and Fleischer 2008], of the behavior of a tatonnement price update rule in Ongoing Fisher Markets. The prior work showed fast convergence toward an equilibrium when the goods satisfied the weak gross substitutes property and had bounded demand and income elasticities. The current work shows that fast convergence also occur...

UNLABELLED Our understanding of etiology and pathogenesis of many disorders, corneal included, greatly relies on existing knowledge in human biochemistry and biophysics. This study was aimed at chemical mapping of normal and keratoconic corneas. MATERIAL AND METHODS Modern methods of analytical chemistry, such as X-ray fluorescence and energy-dispersive X-ray spectroscopy on the basis of scan...

A 19-year-old man presented with a 3-month history of excessive grinning. Examination revealed unrestrained grinning and mild symmetric parkinsonism. Wilson disease was suspected and confirmed by the presence of Kayser-Fleischer ring (figure), suggestive brain MRI (figure), low ceruloplasmin, and high urinary copper levels. Wilson disease is a disorder of copper metabolism characterized by hepa...