Ring1 and YY1 binding protein (RYBP), a member of the polycomb group proteins, has been implicated in transcription repression and tumor cell-specific apoptosis. Previously, RYBP has been reported as a putative tumor suppressor in cancer tissues by regulating mouse double minute 2 homolog-p53 signaling. However, the exact role and underlying mechanisms of RYBP in cancer remain to be fully eluci...

BACKGROUND To evaluate the pathological characteristics of invasive margins in early-stage cervical squamous cell carcinomas and their association with other clinicopathological features including clinical outcomes. MATERIALS AND METHODS Patients with FIGO stage IB-IIA cervical squamous cell carcinomas who received surgical treatment and had available follow-up information were identified. Th...

BACKGROUND NET (NocA/Nlz, Elbow, Tlp-1) family members have recently emerged as important players in the development of human cancers. Zinc finger protein 703 (ZNF703), locating on chromosome 8 (8p11.23), a member of the NET/Nlz family of zinc finger transcription factors, had been demonstrated to be a much novel oncogene of several malignancies. This study aimed to investigate the expression o...

MYC associated zinc finger protein (MAZ) plays a key role in regulation of gene expression and tumor development. Studies have shown that deregulated expression of MAZ is closely related to the progression of tumors such as glioblastoma, breast cancer, prostate cancer and liposarcoma. However, the role of MAZ in hepatocellular carcinoma (HCC) has not been fully elucidated. Here, we found that e...

The complete removal of glioblastoma brain tumours is impossible to achieve by surgery alone due the complex finger-like tentacle structure tumour cells and their migration away from bulk at time surgery; furthermore, despite aggressive chemotherapy radiotherapy treatments following surgery, continue grow, leading death patients within 15 months after diagnosis. naturally occurring carnosine di...

We present two patients with a displaced fracture of the small finger metacarpal base, where the shaft of the small finger metacarpal was wedged between the bases of the ring and small finger metacarpals. The striking appearance on radiographs led to initial recommendations for surgery, but both patients preferred non-operative treatment and did well in the short term without surgery

finger prints of 68 patients with down's syndrome and 93 controls have been collected and analyzed for topological of formulation of finger tip patterns suggested by loesch (1975). the results showed that there may be great differences in the dictionary of the finger patterns of the patients and their controls. mean lunar and radial patterns showed mostly significant differences among the patie...

abstract  background: the goal of this report is to show our results with extension block technique for treatment of mallet fracture. the indications for this technique were the presence of a large bone fragment, and palmar subluxation.  methods: we retrospectively assessed the results of treatment in 14 mallet fractures  which have been treated by extension block technique to determine the ran...

we present two patients with a displaced fracture of the small finger metacarpal base, where the shaft of the small finger metacarpal was wedged between the bases of the ring and small finger metacarpals. the striking appearance on radiographs led to initial recommendations for surgery, but both patients preferred non-operative treatment and did well in the short term without surgery