The effect of milled and micronized lactose fines on the fluidization and in vitro aerosolization properties of dry powder inhaler (DPI) formulations was investigated, and the suitability of static and dynamic methods for characterising general powder flow properties of these blends was assessed. Lactose carrier pre-blends were prepared by adding different lactose fines (Lactohale 300, 230 and ...

The aim of the study was to investigate how the fine particle content of lactose carriers prepared with different types of lactose fines regulates dry powder inhaler (DPI) formulation performance of a cohesive batch of micronised budesonide. Budesonide formulations (0.8 wt%) were prepared with three different lactose carriers (Lactohale (LH) LH100, 20 wt% LH210 in LH100 and 20 wt% LH300 in LH10...

Sandcrete block, being one of the most important building materials, has become very expensive nowadays and it’s on high demand in Nigeria. In order to reduce its cost and probably increase the compressive strength, this research was conducted to assess the suitability of granite fines as partial replacement for sand in sandcrete block production. The mix proportion (1:6) was used for batching ...

The present study deals with the utilization of fines generated from comminution process (crushing, grinding and screening) of the Run of Mines into value added products i.e. fluxed iron ore pellets. The study comprises to understand the physical and mechanical behavior of five distinguished chemical compositions of green and dried iron ore pellets with respect to a typical Mini Blast furnace (...

Introduction: Interpretation of data acquired at Ceres by the Dawn spacecraft demands a model for the evolution of Ceres’ structure and composition to date. In a recent paper [1], we presented such a model, consistent with pre-Dawn observations and preliminary data returned by Dawn. Here, we describe this model, compare its physico-chemical outcomes to reported observations, and outline possibl...

Objective- This study was conducted to make a full understanding of the anatomic and ultrasonographic characteristics of digestive canal in Persian Sturgeon and provide standard approaches for performing digestive tract ultrasonography on this sturgeon species.Design - Experimental studyAnimals - 30 mature Persian sturgeons (Asipenc...

This paper analyzes the joint design of innovation and competition policy. It focuses on collusion sustainability changes due to implementation of antitrust fines and R&D subsidies in an extension of a model by Miyagiwa (2009). Generic subsidies for R&D are found not to facilitate collusion, while additional subsidization to research joint ventures (RJVs) can be collusion facilitating. We also ...

We study the optimal assignment of policy instruments at regional and interregional levels, for international carbon emissions trading with noncompliant polluters. We demonstrate that decentralization of regional emission quotas is socially optimal, when fines and interregional income transfers are implemented by intergovernmental authorities after regional policy making, because regional regul...

This work investigates the effects of different seeding strategies and residence time characteristics on the dynamics of a Mixed Suspension Mixed Product Removal (MSMPR) crystallizer equipped with a fines dissolution unit and applied to continuous preferential enantioselective crystallization. The fines dissolution is included as recycle streams around the MSMPR crystallizer. Moreover, primary ...