Filariases are a group of vector – borne parasitic diseases of humans and other animals, caused by long, threadlike worms (hence the name “filaria” from Latin) that in their mature adult stages reside in the lymphatics or in connective tissue. Of the eight filarial parasites that commonly infect man three species account for most of the pathology associated with these infections: the lymphatic ...

ANDERSON, P. J. S. and VERSTER, ANNA, 1971. Studies on Dictyocaulus filaria. I. Modifications of laboratory procedures. Onderstepoort]. vet. Res. 38 (3), 181-184 (1971). Techniques used in a study of the life-cycle of Dictyocaulus filaria (Rudolphi, 1809) are described. First stage larvae migrate from faecal pellets placed in water. Infective larvae are cultured in clean water at room temperatu...

We compared the age profiles of infection and specific antibody intensities in two communities with different transmission levels in East Africa to examine the contribution of humoral responses to human immunity to the vector-borne helminth Wuchereria bancrofti. The worm intensities were higher and exhibited a nonlinear age pattern in a high-transmission community, Masaika, in contrast to the l...

Officiating Professor of Descriptive and Surgical Anatomy and Clinical Surgery, Calcutta Medical College, and Second Surgeon, Medical College Hospital. The following case, which recently came under my observation; illustrates a peculiar form of scrotal disease of not infrequent occurrence in India, to which Dr. T. Lewis has added a new interest by the discovery of the filaria sanguinis hominis ...

Wolbachia is an obligatory intracellular endosymbiotic bacterium, present in over 20% of all insects altering insect reproductive capabilities and in a wide range of filarial worms which is essential for worm survival and reproduction. In Egypt, no available data were found about Wolbachia searching for it in either mosquitoes or filarial worms. Thus, we aimed to identify the possible concurren...

Litomosoides sigmodontis is the only filaria which develops from infective larvae into adults in immunocompetent laboratory mice. Depletion of CD4+ T cells from infected BALB/c mice resulted in worm and microfilarial burdens significantly higher than those of infected controls. Th2 cytokines, eosinophilia, and immunoglobulin E, which were strongly induced in infected controls, were diminished i...