OBJECTIVE The purpose of this study is to highlight the evidence of signs and symptoms of craniomandibular disorders (CMD) in patients suffering from fibromyalgia. MATERIALS AND METHOD The study has been carried out from May 2011 to May 2015, recruiting a sample of fibromyalgia patients at the Department of Neurophysiopathology at the hospital Policlinico in Bari. Among the 150 examined patie...

Fibromyalgia is a form of non-articular rheumatism in which inflammatory cytokines seem to be involved. However, there is still no analytical specific diagnostic criterion for this disease. The aim was to examine a possible role of fractalkine as a biomarker in fibromyalgia. Plasma levels of soluble fractalkine were compared between women diagnosed with fibromyalgia (n=17) and healthy women (n=...

Significant evidence exists for central sensitization in fibromyalgia, however the cause of this process in fibromyalgia-and how it relates to other known abnormalities in fibromyalgia-remains unclear. Central sensitization occurs when persistent nociceptive input leads to increased excitability in the dorsal horn neurons of the spinal cord. In this hyperexcited state, spinal cord neurons produ...

background: many alternative interventions are practiced in an effort to reduce symptoms of fibromiyalgia. the aim of this study was to determine the effects of sleep and touch therapy accompanied by music and aromatherapy on the symptoms of fibromyalgia and depression. methods: the study was carried out between september 2009 and march 2011 in the physical medicine and rehabilitation polyclini...

• Vol 10 • January 2008 Fibromyalgia and Autoimmune Diseases Fibromyalgia syndrome is a commonly encountered disorder characterized by chronic widespread musculoskeletal pain and related symptoms along with multiple painful tender points [1]. The pathogenesis of fibromyalgia is not entirely understood, although the current concept views the syndrome as the result of central nervous system malfu...

Objective: Saffron was found efficient and safe in treatment of neuropsychiatric disorders, in particular depression. We compared the efficacy of saffron with duloxetine in treatment of patients with fibromyalgia. Materials and Methods: In this double-blind parallel-group clinical trial, outpatients with fibromyalgia were randomized to receive either saffron 15 mg or duloxetine 30 mg starting w...

Sir, In their elegant study, Üçeyler et al. (2013) provide objective evidence of small fibre neuropathy in patients with fibromyalgia. They conclude that fibromyalgia may be a neuropathic pain syndrome (Üçeyler et al., 2013). Small fibre neuropathy is a disorder of the peripheral nerves resulting in sensory changes and sympathetic dysfunction. For years, we have proposed that fibromyalgia is a ...

Background: An association between irritable bowel syndrome (IBS) and small intestinal bacterial overgrowth (SIBO) has been found. Objective: To compare the prevalence and test results for bacterial overgrowth between IBS and fibromyalgia. Methods: Subjects with independent fibromyalgia and IBS were compared with controls in a double blind study. Participants completed a questionnaire, and a la...