Natural or spontaneous fibrinolytic activity of the blood is due to a labile activator which is stabilized by fibrin formation. Current methods of measuring spontaneous fibrinolysis require either low temperature centrifugation when plasma is used or photography when diluted whole blood is used and neither is available in the average laboratory. A method of measuring fibrinolytic activity in bl...

Fibrinolytic activity and platelet adhesiveness are normal in cases of angina pectoris and healed myocardial infarction, whereas fibrinolytic activity is diminished in acute myocardial infarction. Exercise increases fibrinolytic activity in normal people but the effect on it of submaximal exercise in patients with ischaemic heart disease is not known. Resting platelet adhesiveness and fibrinoly...

Fibrinolytic enzymes are agents that dissolve fibrin clots. These fibrinolytic agents have potential use to treat cardiovascular diseases, such as heart attack and stroke. In the present article, a fibrinolytic enzyme producing Pseudoalteromonas sp. IND11 was isolated from the fish scales and optimized for enzyme production. Cow dung was used as a substrate for the production of fibrinolytic en...

Background Despite the widespread use of fibrinolytic therapy and the numerous reports on its bleeding complications, spontaneous hemarthrosis following fibrinolytic therapy is quite rare. Case Report We describe in this report a patient with no previous history of articular disease who developed a spontaneous right knee bloody effusion following fibrinolytic therapy using rt-PA for acute ST-el...

The urine and serum fibrinolytic activity were measured in dogs following whole body radiation ranging from 450 to 800 r generated by 1,000 kv. and 250 kv. machines. The fibrinolytic activity of the urine showed a precipitate rise 4 to 5 days before death in all dogs with pulmonary hemorrhage as the main cause of death. The fibrinolytic activity of the serum showed a similar rise, which was mos...

Bacillus sp. can biosynthesize fibrinolytic enzymes. Culture conditions and nutrient sources are important factors affecting microbial growth production of the Fibrinolytic enzyme. Therefore, we investigated culture strain ES4, such as temperature, pH, C source (glucose, sucrose, glycerol, maltose), N (yeast extract, meat content, peptone, tryptone), metal ions (Ca 2+ , Mg Mn Zn K + Fe Cu ), ti...

Fibrinolytic treatment is the standard of care for eligible patients presenting early with acute ST segment elevation myocardial infarction (MI) to hospitals where rapid triage to primary angioplasty is unavailable. Although fibrinolytic treatment of elderly patients is generally accepted, a recent paper raised questions about its safety and efficacy. In this editorial, we will review the relev...

The fibrinolytic enzyme system is co] important in the removal of pathologi fibrin (Astrup, 1956). In the later s disease excessive fibrinous exudato formed. A defect in the fibrinolytic e of lung tissue which may be importan genesis of the fibrinous intra-alveolar occurs in renal failure has been report Stalker, and Ogston, 1962). We des results of a study of the fibrinolytic sys and urine in ...

The effect of local and whole-body heating and cooling on plasma fibrinolytic activity has been investigated in 59 subjects. An increase in whole-body temperature and both local cooling and heating increased the fibrinolytic activity. The results demonstrate that the application of local heat or cold will produce a local increase in fibrinolytic activity which is independent of general factors ...