The aldehyde tag is appropriate to selectively label proteins, prepare antibody-drug conjugates or immobilize enzymes antibodies for biotechnological and medical applications. cysteine within the consensus sequence CxPxR of specifically oxidized by formylglycine-generating enzyme (FGE) non-canonical electrophilic amino acid Cα-formylglycine (FGly). Subsequent reductive amination a common method...

in this paper, we first define spaces of single difference sequences defined by a sequence of orlicz functions without convexity and investigate their properties. then we extend this idea to spaces of double sequences and present a new matrix theoretic approach construction of such double sequence spaces.

A Moroccan Houbara Bustard pedigree was analyzed to evaluate the genetic variability in captive breeding population using genealogical approaches. The whole Houbara breeding flock (WP) for the period 1993-2004 was made up of 531 birds comprising 346 females and 185 males. The reference population (RP) comprised 198 individuals ready for reproduction from 2000 to 2004 cohorts. The corresponding ...

in this paper, we deal with the subdierential concept onhadamard spaces. flat hadamard spaces are characterized, and nec-essary and sucient conditions are presented to prove that the subdif-ferential set in hadamard spaces is nonempty. proximal subdierentialin hadamard spaces is addressed and some basic properties are high-lighted. finally, a density theorem for subdierential set is establi...

introduction of modern architecture in iran and its popularization in 1950s and after, brought some new concepts in everyday life of iranian women, among which was “kitchen as heart of home-life”. younger members of current generation are grown in these modernized spaces while a bit older ones have experienced houses of traditional style. this study is designed to explore what previous concept ...

Fabry disease may be treated by enzyme replacement therapy (ERT), but the impact of chronic kidney (CKD) on response to remains unclear. The aim present study was analyse incidence and predictors clinical events in patients ERT. Multicentre retrospective observational analysis diagnosed with ERT for disease. primary outcome first renal, neurological or cardiological death during a follow-up 60 ...