A study was carried out to examine the independence from starting prebronchodilator FEV1 of four indices commonly used to express airflow (FEV1) reversibility in response to bronchodilators. In 121 patients with chronic airflow obstruction with a mean prebronchodilator FEV1 of 1.81 (43.9% of predicted values) the change in FEV1 expressed as a percentage of the patient's predicted FEV1 was the l...

BACKGROUND There is no agreement on how a bronchodilator response should be expressed. Ideally, the index used should be able to distinguish asthma from chronic obstructive lung disease and be independent of initial FEV1. METHODS Two hundred and seventy four adults (aged 18-60 years) outpatients with obstructive airways disease were studied. Patients were divided into syndrome groups on the b...

BACKGROUND In occupational asthma continued workplace exposure to the causative agent is associated with a poor prognosis. However, there is little information available on how rapidly lung function declines in those who continue to be exposed, nor how removal from exposure affects lung function. METHODS Forced expiratory volume in 1 second (FEV1) was studied in 156 consecutive subjects with ...

I read the paper by Taylor-Robinson et al with interest with regard to modelling the decline in forced expiratory volume in 1 second (FEV1) in patients with cystic fibrosis (CF). The authors have made the assumption that expressing spirometry results as a per cent of predicted (PP) is a valid way to use lung function over a wide age range. Young adult patients with cystic fibrosis die with abso...

In 2022, Poland joined the elite group of countries where CFTR modulators (mCFTR) are reimbursed. The aim this prospective study was analysis selected nutritional and pulmonary function parameters their impact on patient health-related quality life in CF children before 3 months after introduction mCFTR therapy. patients aged 2–18 consecutively enrolled program were assessed during trimonthly v...

introduction: the association between asthma and sinonasal disease has been established for years. as sinonasal disease is one of the factors that exacerbates asthma, effective treatment of this disorder may also improve and stabilize the asthmatic condition. this study examines the outcome of endoscopic sinus surgery (ess) on asthmatic patients with massive nasal polyposis.   materials and met...

BACKGROUND Forced expiratory volume in 1 second (FEV1)/forced expiratory volume in 6 seconds (FEV6) has been proposed as an alternative to FEV1/forced vital capacity (FVC) for detecting airway obstruction. A fixed cut-off value for FEV1/FEV6 in a Korean population is lacking. We investigated a fixed cut-off for FEV1/FEV6 as a surrogate for FEV1/FVC for detecting airway obstruction. MATERIALS ...

We examined the hypothesis that a forced expiratory volume in one second (FEV1) manoeuvre (and the preceding deep inhalation) before inhalation of methacholine might influence FEV1 measured after methacholine, if the time between measurements was short. Six to nine healthy subjects inhaled a single dose of methacholine, known to cause about 20% decrease in FEV1, on different days in different t...

Asthma is the most common chronic pulmonary disease in world, affecting more than three hundred million people from different races and age groups. Childhood asthma considered one of main causes increased healthcare expenditures, particularly developing countries. Spirometry essential commonly used lung function test. It mainly for evaluation to obtain reliable data detection diseases, such as ...