Fetal growth restriction or intrauterine growth restriction is one of the leading causes of perinatal mortality and morbidity in newborns. Fetal growth restriction is a complex multifactorial condition resulting from several fetal and maternal disorders. The objective of this study was twofold: first to examine the correlation between maternal parameters such as body mass index (BMI), nutrition...

To evaluate the prediction of low birth weight (BW) using longitudinal individual fetal growth measurement in suspected late restriction (FGR). This is a secondary analysis from multicentre observational study (TRUFFLE2) April 2017 to July 2018.Women at 32–36 weeks with suspect FGR (estimated (EFW) p40) were monitored by 2-weekly biometry and Doppler asses...

Birth weight remains one of the most important measures we have of the health status of a population, and is a strong predictor of both neonatal mortality and morbidity. It reflects maternal nutritional status and fetal growth rates in the antenatal period. Although a large number of physiological and pathological variables can affect the growth rate, for most cases of growth-restricted fetuses...

Intrauterine growth restriction (IUGR) is interconnected with developmental programming of lifelong pathophysiology. IUGR is seen in human multifetal pregnancies, with stepwise rises in fetal numbers interfering with placental nutrient delivery. It remains unknown whether fetal blood analyses would reflect fetal nutrition, liver, and excretory function in the last trimester of human or ovine IU...

The concentrations of plasma glucose, insulin, growth hormone, and immunoreactive growth hormone-like substance in subhuman primate fetal and maternal plasma were examined after the intravascular administration of glucose, arginine, or tolbutamide to the fetus. Cannulation of interplacental vessels permitted studies on the fetus in utero without disruption of fetal-placental-maternal anatomic i...

BACKGROUND Data from the study of the British 1958 birth cohort, National Child Development Study (NCDS), has allowed wider investigation of the relationship between retarded fetal growth and risk of adult hypertension. METHODS A history of self-reported hypertension was related to fetal growth in 3308 parous cohort members. Fetal growth, the measure used, is the difference in actual birthwei...

Empirical studies have shown that fetal growth and activity can be affected by several risk factors, such as maternal anxiety, depression and tobacco or alcohol consumption. Caffeine intake has received less attention in the literature, as well as the analysis of the mutual interplay of the range of such risk factors. This study aimed to examine effects of mother's coffee intake and associated ...

BACKGROUND Previous research suggests, though not consistently, that maternal psychological distress during pregnancy leads to adverse birth outcomes. We investigated whether maternal psychological distress affects fetal growth during the period of mid-pregnancy until birth. METHOD Pregnant women (n=6313) reported levels of psychological distress using the Brief Symptom Inventory (anxious and...