OBJECTIVE To report a series of cases of ulceration of the oral mucosa linked to direct contact with ferrous sulfate in elderly patients. CASE SUMMARY The first case report concerns the occurrence of widespread oral ulceration in an 87-year-old woman with Alzheimer's disease. The ulceration extended from the side of the tongue to the floor of the mouth. No clear explanation was found and vari...

Leghemoglobin may be isolated from soybean root nodules as a complex, leghemoglobin a-X of ferric leghemoglobin with a low molecular weight ligand X. That complex dissociates at neutral or alkaline pH and the ligand X may be separated from free leghemoglobin by ultrafiltration. The complex is regenerated by combining ferric leghemoglobin with X. The affinity of ferrous leghemoglobin for X is ve...

iron oxide is an important biological agent that has a key role in medical processes; however, the mechanism whereby it provides iron for human and animal cells and its biological uses remains unclear. we aimed to evaluate the effects of oral iron oxide on serum iron status and compare the results with those of iron sulfate as a reference salt. fifteen adult rabbits were divided into 3 groups o...

The concentrations of ferrous and ferric ions change dramatically during the course of the batch experiments usually performed to study the kinetics of the bacterial oxidation of ferrous ions and sulfide minerals. This change in concentration of the iron species during the course of the experiment often makes it difficult to interpret the results of these experiments, as is evidenced by the lac...

Cysteine plays a key role as a metal ligand in metalloproteins. In all well-recognized cases, however, it is the anionic cysteinate that coordinates. Several cysteinate-ligated heme proteins are known, but some fail to retain thiolate ligation in the ferrous state, possibly following protonation to form neutral cysteine. Ligation by cysteine thiol in ferrous heme proteins has not been documente...

Porphyria cutanea tarda (PCT) is characterized biochemically by excessive hepatic synthesis and urinary excretion of uroporphyrin I. Clinical evidence has implicated iron in the pathogenesis of PCT. The synthesis of the normally occurring isomer of uroporphyrin, namely uroporphyrin III, from porphobilinogen (PBG) requires two enzymes; uroporphyrinogen I synthetase and uroporphyrinogen III cosyn...

Interest in the aging of metal hydroxide has increased greatly during the past few years and it is due, no doubt, mainly to the fact that certain metal hydroxides have become useful for the isolation of enzymes and vitamins. The selective adsorption properties of these hydroxides, aluminum hydroxide for example, make them suitable for these purposes. Their surface forces make it possible to sep...

the oxidation of ferrous iron (fe2+) in solution using acidithiobacillus ferrooxidans has industrial applications exclusively in the regeneration of ferric iron (fe3+) as an oxidizing agent for the removal of hydrogen sulfide from waste gases, desulfurization of coal, leaching of non-ferrous metallic sulfides and treatment of acid mine drainage. the aim of this investigation was to increase the...

BACKGROUND Some pregnant women discontinue iron supplements consumption due to Gastrointestinal (GI) complications, whereas pregnancy induces the same complications physiologically. OBJECTIVES The aim of the present study was to assess GI complications of ferrous sulfate in pregnant women. PATIENTS AND METHODS This randomized, double-blind, placebo-controlled clinical trial was performed on...