In this study, kinetics of attachment and internalization of feline infectious peritonitis virus (FIPV) serotype I strain Black and serotype II strain 79-1146 were determined in feline monocytes from two cats and in Crandell feline kidney (CrFK) cells. Attached FIPV I (Black) particles were observed on almost all monocytes. Within 1 h, 17 particles were bound per cell and, within 1 min, 89 % of...

This synopsis is taken from a much larger and more scientifically comprehensive review of FIP literature from the period 1963 through 2008. Although more technical than the Q&A format review also provided on the SOCKFIP website, it should prove helpful to those people with the desire to obtain more in depth knowledge of this disease. It is also hoped that the inclusion of references will demons...

Anti-idiotypic monoclonal antibody 409.5.3 is raised against an antibody that neutralizes feline infectious peritonitis virus. This antibody, used as an immunogen, elicits the production of anti-anti-idiotypic antibodies that in turn neutralize the virus. The crystal structure of the complex between anti-idiotypic Fab 409.5.3 and idiotypic Fab fragment of virus-neutralizing antibody has been so...

http://www.revistadechimie.ro 1055 Feline infectious peritonitis (FIP) is viral, lethal disease caused by a feline coronavirus, with immune-mediated mechanism. The disease has been reported in a variety of species, mountain lion (Felis concolor), caracal (Caracal caracal), lion (Panthera Leo), tiger (Panthera tigris), jaguar (Panthera onca), sand cat (Margarita felis), shaving ( Lynx lynx) and ...

Feline infectious peritonitis (FIP) is a lethal immunopathological disease caused by feline coronaviruses (FCoVs). Here, we describe a reverse genetics approach to study FIP by assessing the pathogenicity of recombinant type I and type II and chimeric type I/type II FCoVs. All recombinant FCoVs established productive infection in cats, and recombinant type II FCoV (strain 79-1146) induced FIP. ...

375 A 1-year-old castrated male domestic shorthaired cat was presented for evaluation of a 10-day history of lethargy, anorexia, decreased water consumption, and apparent discomfort. A complete blood count and serum chemistry profile revealed hypoalbuminemia, leukocytosis, and neutrophilia. The results of a combined ELISA test for feline leukemia virus and feline immunodeficiency virus were neg...