Earlier reports (Y. Kawaguchi, R. Bruni, and B. Roizman, J. Virol. 71:1019-1024, 1997; Y. Kawaguchi, C. Van Sant, and B. Roizman, J. Virol. 72:1731-1736, 1998) showed that herpes simplex virus 1 (HSV-1) infection causes the hyperphosphorylation of translation elongation factor 1delta (EF-1delta) and that the modification of EF-1delta is the consequence of direct phosphorylation by a viral prote...

Feline herpesvirus 1 (FeHV-1) is an alphaherpesvirus that causes feline viral rhinotracheitis, an important viral disease of cats on a worldwide basis. Acute FeHV-1 infection is associated with both upper respiratory and ocular signs. Following the acute phase of the disease lifelong latency is established, primarily in sensory neuronal cells. As is the case with human herpes simplex viruses, l...

FELINE HERPESVIRUS Despite the ready availability of vaccines and antiviral drugs effective against feline herpesvirus type 1 (FHV-1), this virus remains a major, common, and frustrating pathogen of cats worldwide. FHV-1 has been associated with acute, chronic, and recurrent conjunctivitis, ulcerative and stromal keratitis, corneal sequestrum, eosinophilic keratitis, anterior uveitis, dermatiti...

Two field isolates of feline herpesvirus type 1 (FHV-1) designated as 00-015 and 00-035, were obtained from cats diagnosed as feline viral rhinotracheitis (FVR) in Japan. To analyze the character of recent FHV-1, these two isolates and our laboratory strain C7301 were inoculated experimentally to specific-pathogen-free cats. Although all cats showed typical FVR symptoms, more severe clinical sy...

Incidences of major feline viral diseases provide basic information for preventing disease in cats. Despite the growing interest diseases, sero-surveillances have been lacking. In this study, we analyzed diagnoses and conducted a sero surveillance panleukopenia virus (FPV), calicivirus (FCV), herpesvirus-1 (FHV-1), infectious peritonitis (FIPV) Korean Of 204 confirmed cases since 2015, numbers ...