Feline Viral Upper Respiratory Tract Disease Feline viral upper respiratory tract disease is typified by signs of rhinosinusitis, conjunctivitis, lacrimation, salivation, and/or oral ulcerations. The principal causative agents are feline herpesvirus type 1 (FHV-1 ) and feline calicivirus (FCV). These viruses are host-specific and pose no known human risk. Other infectious agents (e.g. Bordetell...

Mammary tumors are common in cats. As mutations in human Brca2 confer an increased risk of breast cancer, the full-length cDNA of the feline homologue of Brca2 was sequenced to obtain a basis for studying the relationship between its function and susceptibility to mammary tumors. The feline Brca2 cDNA is 10 kb long, and encodes 3,371 amino acids. The amino acid sequence of feline Brca2 shares l...

Although feline neonatal isoerythrolysis is rare, associated mortality rate is high. It results from mating of type B blood queens with type A or AB blood toms. A comprehensive review on feline blood types and feline neonatal isoerythrolysis physiopathology, clinical features, diagnosis, treatment, and prevention is covered.

Previously, we reported that a feline T lymphoid cell line, FL74 cells, was very sensitive to feline parvovirus (FPV) infection. In the present study, we developed new quantitative methods for detection of FPV and virus neutralizing antibody against FPV using FL74 cells. The methods presented here were very simple and applicable to both canine parvovirus and feline panleukopenia virus.

OBJECTIVES To develop a composite measure pain scale tool to assess acute pain in cats and derive an intervention score. METHODS To develop the prototype composite measure pain scale-feline, words describing painful cats were collected, grouped into behavioural categories and ranked. To assess prototype validity two observers independently assigned composite measure pain scale-feline and nume...

feline infectious peritonitis virus (fipv) is ubiquitous in domestic cats, especially in young cats and multi-cat environments. in the present study, a total of 248 companion cats of different ages were examined for serum antibody detection of fipv by immunochromatography assay. the cats were selected from those referring to veterinary hospital of ahvaz university, southwestern iran from decemb...

Several infectious diseases are the cause or associated with the female and occasionally the male reproductive system of the cat.1>2,3,4,5,6^7,a Most notable are the viral diseases that cause infertility, embryonal-fetal death and resorption, malformations, abortion, mummification, stillborns and kitten neonatal death. Two classical viral infections, panleukopenia and feline viral rhinotracheit...

A feline monocytic cell line was established from a venous blood sample obtained from a healthy male donor cat. The cloned cells, temporarily named FLMo/K02, were successively passaged in vitro with cell growth medium consisting of RPMI-1640 supplemented with 10% heat-inactivated fetal calf serum. Non-specific esterase and acid phosphatase, as marker enzymes, were clearly demonstrated by cytoch...

The 15,000-molecular-weight polypeptide (p15) of feline leukemia virus (FeLV) was shown to impair normal lymphocyte function in vitro and to abrogate immunity to feline oncornavirus disease in vivo. FeLVp15 suppressed concanavalin A-induced blast transformation of normal feline lymphocytes by 68%, while other virion proteins had no effect. p15 suppression was not due to toxicity, nor was p15 a ...

It is likely that the murine response to human recombinant TNFα (hrTNFα) may generate antibodies (Ab) to epitopes present in TNFα from other species. Here, we demonstrate that F5 antihrTNFα monoclonal antibody (mAb) recognizes feline TNFα while E8 anti-hrTNFα mAb failed to do so. In order to demonstrate that E8 and F5 mAb recognize different epitopes in the hrTNFα molecule, a constant concentra...