Because chronic ethanol ingestion decreases pulmonary clearance of Streptococcus pneumoniae in rats, and extracellular antipneumococcal factors in rat surfactant are important in the early clearance of pneumococci from the rat alveolus, the effects of ethanol ingestion on surfactant bactericidal activity were investigated. Normal surfactant from chow-fed rats showed potent anti-pneumococcal act...

In search of an adequate model for the human metabolic syndrome, the metabolic characteristics of Wistar rats were analysed after being submitted to different protocols of high fructose ingestion. First, two adult rat groups (aged 90 d) were studied: a control group (C1; n 6) received regular rodent chow (Labina, Purina) and a fructose group (F1; n 6) was fed on regular rodent chow. Fructose wa...

Dieta.—Male Wistar rats were placed on a semi synthetic diet at weaning, and the food consump tion of each was measured. A week later each rat was paired with one of equal body weight and food consumption. At this time one rat of each pair was designated as the experimental rat which would receive a tumor transplant; the other rat, his pair fed control, consumed the amount of diet eaten by th...

Effects of 3 days of starvation on catabolism of leucine and a-ketoisocaproic acid in skeletal muscle have been examined using a perfused hindquarter preparation. The perfusate contained 0.2 l l l ~ [l-"C]or @JClleucine, all other amino acids at approximately reported rat plasma concentrations, and 5.5 mM glucose. During 90 min of recirculation, there was net release into the perfusate of total...

the effect of dietary sucrose on dna formation in rat liver and kidney compared with that of starch was studied. male, weanling rats were fed for 6 and 14 days on diets containing 68% 'sucrose or 68% starch, and liver and kidneys were examined for 1ilie amount and rate of formation of dna; and also for content of fat, protein, and moisture. food intake and weight gain were estimated. sucrose fe...

Female brown-banded cockroaches, Supella longipalpa (F.) (Dictyoptera : Blattellidae), failed to elevate consumption rates when fed a 5~o protein diet compared with females fed either 25~o protein or commercial rat food. Adult performance was directly influenced by dietary protein level: Females fed 65 ~o protein died rapidly, while in females fed 5 ~o protein feeding and reproductive rates wer...

BACKGROUND Obesity is associated with unfavorable alternations in plasma lipid profile and a broad spectrum of cardio-metabolic disorders. Proprotein convestase subtilisin kexin type 9 (PCSK9) is a novel circulating protein that promotes hypercholesterolemia by decreasing hepatic low lipoprotein density receptor (LDLR) protein. However, the relationship between PCSK9 concentration and lipid pro...

OBJECTIVE To determine whether exaggerated natriuresis and exaggerated renal sympathoinhibition during volume loading constitute an intermediate phenotype in spontaneously hypertensive rats. DESIGN The borderline hypertensive rat, the F1 of a cross between a spontaneously hypertensive rat and a normotensive Wistar-Kyoto rat, is a NaCl-sensitive model of genetic hypertension. In addition to hy...