background and aim: the aim of this study was to determine the effect of legume intake in therapeutic lifestyle change (tlc) on fasting insulin, fasting blood glucose, hba1c and homeostasis model assessment insulin resistance (homa-ir) in patients with type 2 diabetes. materials and methods: in this randomized crossover trial, 31 subjects with type 2 diabetes in the age range of 50 to 80 years ...

INTRODUCTION In the 1980s, the idea evolved that some individuals with normal weight (Metabolically Obese, Normal-Weight), who probably have increased abdominal fat, have metabolic disturbances related to obesity. This observation initiated the concept of the metabolically obese but normal-weight syndrome (MONW). Since then, there have been only a few studies in non-obese subjects. MONW men and...

OBJECTIVES Follistatin-like 1 (Fstl1) is a circulating glycoprotein that plays a crucial role in cardiovascular diseases and inflammation-related disorders. We have shown that Fstl1 acts as an anti-inflammatory factor that protects against ischemic heart disease and chronic kidney disease. Here we examined whether plasma level of Fstl1 associates with markers of inflammation and oxidative stres...

OBJECTIVE Difficulties in measuring insulin sensitivity prevent the identification of insulin-resistant individuals in the general population. Therefore, we compared fasting insulin, homeostasis model assessment (HOMA), insulin-to-glucose ratio, Bennett index, and a score based on weighted combinations of fasting insulin, BMI, and fasting triglycerides with the euglycemic insulin clamp to deter...

OBJECTIVES To identify the fasting glucose/leptin ratio as a new simple method for the detection of insulin resistance in Iraqi diabetes mellitus patients, and to examine its usefulness as a new marker for insulin resistance. METHODS A case control study conducted at the National Diabetes Center, College of Medicine at Al-Mustansiryia University from 1 August 2008 to 30 January 2010. An enzym...

OBJECTIVE To determine the prevalence of metabolic syndrome and insulin resistance in Thai women with polycystic ovary syndrome (PCOS). MATERIAL AND METHOD Oral glucose tolerance tests were performed in 70 PCOS women. Blood was taken for the measurement of fasting insulin, 2-hr postprandial insulin, lipid profiles, testosterone and sex hormone binding globulin RESULTS The prevalence of meta...

AIM To determine whether fasting serum uric acid is associated with the insulin sensitivity index or with other anthropometric, metabolic or environmental features of the insulin resistance syndrome in a population-based sample of young healthy Caucasians. METHODS The protocol included 380 unrelated Caucasian subjects (age 18-32 years) who had their insulin sensitivity index and glucose effec...