Idealized laboratory experiments reported in the literature have been designed to simulate specific physical and chemical conditions. These laboratory conditions have allowed researchers to control the variables which affect the behavior of contaminants in the subsurface and to identify the mechanisms which are likely to occur in the field. An understanding of the various mechanisms of facilita...

We analyze transport through conical channels that is driven by the difference in particle concentrations on the two sides of the membrane. Because of the detailed balance, fluxes of noninteracting particles through the same channel, inserted into the membrane in two opposite orientations, are equal. We show that this flux symmetry is broken by particle-particle interactions so that one of the ...

Idealized laboratory experiments reported in the literature have been designed to simulate specific physical and chemical conditions. These laboratory conditions have allowed researchers to control the variables which affect the behavior of contaminants in the subsurface and to identify the mechanisms which are likely to occur in the field. An understanding of the various mechanisms of facilita...

We present an analytically solvable model for self-assembly of a molecular complex on a filament. The process is driven by a seed molecule that undergoes facilitated diffusion, which is a search strategy that combines diffusion in three dimensions and one dimension. Our study is motivated by single-molecule-level observations revealing the dynamics of transcription factors that bind to the deox...

Changing the internal structure of a program without changing its behavior is called restructuring. This paper presents a transformation called tuck for restructuring programs by decomposing large functions into small functions. Tuck consists of three steps: Wedge, Split, and Fold. A wedge—a subset of statements in a slice—contains computations that are related and that may create a meaningful ...

Formalisms and axiomatic theories are designed to support reasoning, they are often intended with a preferred interpretation and a targeted ontology. Questions of proper interpretations and of the possible challenge of an intended interpretation arise when integrating a particular theory in pre-existing formal and ontological settings. This paper reports on an instance of this general problem o...

Turbulent atmospheric conditions represent a challenge to stable flight in soaring birds, which are often seen to drop their wings in a transient motion that we call a tuck. Here, we investigate the mechanics, occurrence and causation of wing tucking in a captive steppe eagle Aquila nipalensis, using ground-based video and onboard inertial instrumentation. Statistical analysis of 2594 tucks, id...

Enhanced transport of trace metal in porous media can occur in the presence of a ligand or "carrier" that has a high affinity for binding the pollutant, is dispersed and mobile in the soil environment, is recalcitrant with respect to microbial degradation, and is acceptable to the public. These aspects of the facilitated transport to trace metals are discussed with respect to a naturally occurr...

Within a living cell, site-specific DNA-binding proteins need to search the whole genome to find a target of ~10-20 bp. That they find the target, and do so quickly, is vital for the correct functioning of the DNA, and of the cell as a whole. The current understanding is that this search is performed via facilitated diffusion, i.e. by combining three-dimensional bulk diffusion within the cytopl...

Purpose: Divergence insufficiency is characterized by esotropia at far distance with symptomatic diplopia, minimal or no deviation near distance, and full ocular duction version. We analyzed the results of bilateral lateral rectus (BLR) tucking in patients divergence insufficiency.Methods: Surgery was performed on persistent diplopia for least 6 months after onset. The surgical were evaluated B...