Background & Aims: Atherosclerosis is a major cause of morbidity and mortality. Adiponectin reducesthe risk of heart disease, and matrix metalloproteinase-9 (MMP-9) is involved in the formation and development of atherosclerotic plaque. The aim of this study was the investigation of the effect of adiponectin on MMP-9 gene expression. It seems this hormone can reduce the risk of atherosclerosis ...

The current study aimed to elucidate the potential involvement of mitochondria-endoplasmic reticulum contact genes in pathogenesis periodontal disease by monitoring levels associated including Mitofusion 1 (MFN1) and MFN2, inositol 1,4,5-trisphosphate receptor (IP3R), chaperone glucose-regulated protein 75 (GRP75), sigma non-opioid intracellular (SIGMAR1) phosphate tensin homolog induced putati...

The inability of T7 to develop in cells of Escherichia coli containing F(+) or substituted F' episomes is a result of the failure to synthesize late proteins; no in vivo translation of mRNA species synthesized by the T7 RNA polymerase occurs. Further experiments have been performed to measure the amount of late mRNA in T7-infected F'(PIF(+)) cells. (We have designated the property of phage inhi...

The Gibberella fujikuroi species complex with Fusarium anamorphs is the causal of diverse diseases of many important plants. Many of the known species in this species complex produce a wide range of secondary metabolites. In this study, morphological characteristics of 46 isolates from rice, maize, sugarcane and onion and phylogenetic relationships of 22 isolates on the basis of ITS1-5.8S-ITS2 ...

viral protein-1 (vp1) is a major capsid protein of coxsakievirus b3 (cvb3) that plays an important role in directing viruses towards permissive cells and acts as a main antigenic site of the virus in eliciting of host immune response, hence it seems vp1 can be considered as a vaccine candidate against cvb3 infection. in this study, cdna of vp1 was prepared, cloned into pet expression vector and...

the green fluorescent protein (gfp) was originally isolated from the jellyfish aequorea victoria that fluoresces green when exposed to blue light. gfp protein is composed of 238 amino acids with the molecular mass of 26.9 kd. the gfp gene is frequently used in cellular and molecular biology as a reporter gene. to date, many bacterial, yeast , fungal, plants, fly and mammalian cells, including h...

the influenza a virus is of global concern for the poultry industry, especially the h5 subtype as it has the potential to become highly pathogenic for poultry and mankind. recently, plant expression systems have gained interest as an alternative for the production of vaccine antigens. the goal of the present study was to investigate the possibility of expressing the ha1 protein in nicotiana tab...

Cyclin F protein, also known as FBXO1, is the largest among all cyclins and oscillates in the cell cycle like other cyclins. Apart from being a G2/M cyclin, cyclin F functions as the substrate-binding subunit of SCFcyclin F E3 ubiquitin ligase. In a gene expression analysis performed to identify novel gene modulations associated with cell cycle dysregulation during HIV-1 infection in CD4+ T cel...