The aetiology of ophthalmoplegia in 15 patients with carotid-cavernous sinus fistula is discussed, and the clinical findings are correlated with angiographic and orbital CT appearances. After closure of the fistula the majority of patients with generalised ophthalmoplegia recovered full ocular movements rapidly, while patients with an isolated abduction weakness required much longer to return t...

Extraocular muscle biopsies from normal individuals and five patients with Graves' ophthalmopathy were analyzed by immunohistochemical staining. Fibroblasts in normal extraocular muscle as well as Graves' extraocular muscles expressed HLA-class II antigens, but the muscle cells did not. There was an increase of interstitial tissue in Graves' extraocular muscles but no visible damage to the musc...

PURPOSE To determine the temporal and spatial expression of Pitx2, a bicoid-like homeobox transcription factor, during postnatal development of mouse extraocular muscle and to evaluate its role in the growth and phenotypic maintenance of postnatal extraocular muscle. METHODS Mouse extraocular muscles of different ages were examined for the expression of Pitx2 by RT-PCR, q-PCR, and immunostain...

2. Which statement concerning the rectus extraocular muscle pulleys is correct? a. The rectus pulleys are composed of rings of cartilage. b. The rectus pulleys are rigidly attached to the walls of the orbit. c. Each rectus pulley receives an insertion from the global layer fibers of its rectus extraocular muscle. d. The global layer fibers of the extraocular muscles do not insert on the pulleys...

1) Studies were made of the accessory abducens nucleus and its relationship to the extraocular muscles besides the retractor bulbi muscles in the rat. 2) All the extraocular muscles had nerve fiber connections from the accessory abducens nucleus besides the retractor bulbi muscles. 3) The relationship between the accessory facial nucleus and accessory abducens nucleus was investigated. The acce...

PURPOSE Insulin-like growth factor 1 (IGF1) and cardiotrophin 1 (CT1) are known to increase the strength of extraocular muscles in adult and embryonic animals, but no information is available for the early postnatal period, when strabismus treatment in humans is most urgent. Here the authors sought to determine whether these trophic factors strengthen juvenile maturing extraocular muscles and g...

Oculomotor disturbances commonly occur as manifestations of Graves’ Oohthalmomthv. We investieated the outcome of this disorderfollowing e&ernal-beam orbital radiotherapy. We conducted a prospective study on 15 patients to assess the extent of ophthalmopathy by clinical evaluation, and measurement of the amplitude of gaze and the thickness of the extraocular muscles on computed axial tomography...

Oculomotor disturbances commonly occur as manifestations of Graves’ Oohthalmomthv. We investieated the outcome of this disorderfollowing e&ernal-beam orbital radiotherapy. We conducted a prospective study on 15 patients to assess the extent of ophthalmopathy by clinical evaluation, and measurement of the amplitude of gaze and the thickness of the extraocular muscles on computed axial tomography...