background: gel polymers are considered as new dosimeters for determining radiotherapy dose distribution in three dimensions. objective: the ability of a new formulation of magic-f polymer gel was assessed by experimental measurement and monte carlo (mc) method for studying the effect of gold nanoparticles (gnps) in prostate dose distributions under the internal ir-192 and external 18mv radioth...

BACKGROUND The combination of external-beam radiotherapy and brachytherapy is used commonly to treat men with prostate cancer. In this analysis, the authors examined the rate of biochemical recurrence (BR) and late grade > or =3 genitourinary (GU) and gastrointestinal (GI) toxicity after treatment with external-beam radiotherapy and brachytherapy in a multiinstitutional, cooperative group setti...

AIMS AND BACKGROUND To evaluate the impact of preoperative chemoradiation on sphincter preservation in patients with low-medium locally advanced resectable rectal cancer treated by four chemoradiation schedules. MATERIALS AND METHODS Between 1990 and 2002, 247 patients were treated according to four schedules of chemoradiotherapy: FUMIR (5-fluorouracil, mitomycin, external beam radiotherapy 3...

PURPOSE To determine the clinical and dosimetric factors that predict prostate-specific antygen (PSA) bouncing following brachytherapy HDR and three-dimensional conformal radiation therapy (3D-CRT) for prostate cancer patients. MATERIAL AND METHODS The evaluated population consisted of 121 prostate cancer patients with a minimum of 5 years of follow-up and at least 6 post-treatment PSA levels...

BACKGROUND Adjuvant radiotherapy is common for uterine corpus cancer patients, yet the long-term carcinogenic effects of different types of radiotherapy have not been studied adequately. METHODS Second primary cancer risks were quantified in a cohort of 60,949 individuals surviving > or = 1 year of uterine corpus cancer diagnosed from 1973 to 2003 in Surveillance, Epidemiology and End Results...

BACKGROUND AND PURPOSE We verified the propriety of our systematic error reduction strategy by means of a computer simulation based on our data of position error with a prone fixation device for prostate IMRT. MATERIALS AND METHODS Computer simulations of the off-line correction method for systematic setup errors based on the portal imaging taken on the first several days of the treatment ses...

PURPOSE To systematically review the evidence for the use of stereotactic radiosurgery or stereotactic fractionated radiation therapy in adult patients with malignant glioma. METHODS Key clinical questions to be addressed in this evidence-based review were identified. Outcomes considered were overall survival, quality of life or symptom control, brain tumor control or response and toxicity. M...

breast cancer is the most common cancer in women after skin cancer. in iran, the presentation age of this cancer is younger than the global average. there are different therapeutic methods for treatment of breast cancer and the choice of treatment depends on the stage of the disease as well as its type and characteristics. therapeutic methods include surgery, radiotherapy, and systemic therapie...

The purpose of this study was to evaluate a methodology to reduce scatter and leakage radiations to patients' surface and shallow depths during conventional and advanced external beam radiotherapy. Superflab boluses of different thicknesses were placed on top of a stack of solid water phantoms, and the bolus effect on surface and shallow depth doses for both open and intensity-modulated radioth...