The current study observed the percentage of peripheral blood (PB) CD4+CD25+ regulatory T cells (Tregs) and the influence of CD4+CD25+ Tregs on the proliferation of naïve CD4 T cells in patients with hyperthyroidism. Furthermore, preliminary discussions are presented on the action mechanism of CD4+CD25+ Tregs on hyperthyroidism attacks. The present study identified that compared with the percen...

Background: Postmenopausal estrogen deficiency increases the incidence of cardiovascular diseases. Although hormone replacement therapy can reduce cardiovascular risk, it is associated with an increased cancer risk. Selective estrogen receptor modulators (SERM), like tamoxifen and related compounds, have mixed estrogen agonistic/antagonistic effects. Tamoxifen may confer significant cardiovascu...

Thyroid disorders both hypo and hyperthyroidism are frequently seen in women, the incidence of hypothyroidism is being much higher than hyperthyroidism. Reported studies in these two conditions on reproductive physiology in women and in experimental female animals have shown that both hypo and hyperthyroidism are associated with delay in onset of puberty, anovulation, various menstrual irregula...

BACKGROUND Hyperthyroidism is associated with increased oxidative stress and oxygen free radical production. Oxygen free radicals are implicated in several signalling pathways leading to vascular pathology. The present study evaluates the extent of aortic oxidative stress in experimental hyperthyroidism. MATERIALS AND METHODS Chronic hyperthyroidism was induced in 20 male Wistar rats; another...

Autoimmune diseases accompanied by the development of hypothyroidism (Hashimoto's thyroiditis) and hyperthyroidism (Graves' disease) are one most common disorders thyroid gland. Hypothyroidism is a clinical syndrome that occurs as result hormone deficiency. Hyperthyroidism excessive activity gland hypersecretion hormones. In simple terms, to achieve euthyroid state in both syndromes, two drugs ...

OBJECTIVES Hyperthyroidism is often associated with various neuromuscular disorders, most commonly proximal myopathy. Peripheral nerve involvement in hyperthyroidism is very uncommon and has rarely been reported. We describe a 29-year-old woman with untreated hyperthyroidism who presented with chronic severe axonal sensory-motor polyneuropathy. Peripheral nerve involvement developed together wi...