Development of the vulva in C. elegans is mediated by the combinatorial action of several convergent regulatory inputs, three of which, the Ras, Wnt and Rb-related pathways, act by regulating expression of the lin-39 Hox gene. LIN-39 specifies cell fates and regulates cell fusion in the mid-body region, leading to formation of the vulva. In the lateral seam epidermis, differentiation and cell f...

BACKGROUND The Japan Society of Clinical Pathology (JSCP) has developed a guideline for common diagnostic test utilization in new primary care outpatients. To determine the scientific and economic validity of the JSCP panel testing system, we analyzed cost-effectiveness parameters of test panels advocated. METHODS The "Essential Laboratory Tests" panel (2) [ELT(2) panel], a package of common ...

To understand the molecular processes underlying aging, we screened modENCODE ChIP-seq data to identify transcription factors that bind to age-regulated genes in C. elegans. The most significant hit was the GATA transcription factor encoded by elt-2, which is responsible for inducing expression of intestinal genes during embryogenesis. Expression of ELT-2 decreases during aging, beginning in mi...

The aim of the study is to review current trends in English Language Teaching (ELT) technologies and methodologies to analyze affordances of an approach proposed by Finardi (in press) and called the Inverted CLIL approach. With that aim, the study reviews ELT technologies and methodologies in general and the Content and Language Integrated Learning (CLIL) approach with the use of Massive Online...

Helicopter landing sites in proximity to the forest fire-risk zones are necessary for the delivery of supplies and fire emergency response teams. In this paper, we initially prepared forest fire risk map using Random Forest algorithm by overlaying the effective factors on fire occurring including vegetation types, physiographic, climatic and human factors. Then, three variants of natural candid...

BACKGROUND The influence of embryo loading time (ELT) and the time interval between embryo loading and embryo transfer (TIEL-ET) on the success of IVF/ICSI is unknown. METHODS In a prospective cohort study, we aimed to ascertain the influence of ELT and TIEL-ET on ongoing pregnancy rate (OPR) and life birth rate (LBR). Data from 603 consecutive embryo transfers between January 2008 and Decemb...

This paper presents an extension of the Latency Time (LT) scheduling algorithm for assigning tasks with arbitrary execution times on a multiprocessor with shared memory. The Extended Latency Time (ELT) algorithm adds to the priority function the synchronization associated with access to the shared memory. The assignment is carried out associating with each task a time window of the same size as...

The technology and experiments planned for rover localization and landing site mapping in the 2003 Mars Exploration Rover (MER) mission are described. We introduce the Mars global and landing site local reference systems. For global rover localization in the Mars body-fixed reference system, a triangulation can be performed using observations of common landmarks on satellite images and the very...

BACKGROUND Simulation-based learning is a common educational tool in health care training and frequently involves instructional designs based on Experiential Learning Theory (ELT). However, little research explores the effectiveness and efficiency of different instructional design methodologies appropriate for simulations. The aim of this study was to compare 2 instructional design models, ELT ...