Background: Candida albicans is one of the most important opportunistic pathogens that suppress immunologic mechanisms of the host. It is speculated that structural and secretory proteins of C. albicans have immunomodulatory effects in cancer. Objective: To evaluate the effects of C. albicans structural and secreted proteins on intratumoral CD4/CD8 ratio as well as the survival rate in BALB/c t...

background: bradford protein assay is popular due to its ease of performance and relative sensitivity. many researchers and laboratories in iran use standard assay of bradford by cuvette. no commercial kit was available for bradford microplate assay in iran. meanwhile, imported bradford commercial kits are very expensive and have a long delivery time in iran. till now no study or document on br...

background: cd52 is a small glycoprotein with a gpi anchor at its c-terminus. cd52 is expressed by normal and malignant t and b lymphocytes and monocytes. there are detectable amounts of soluble cd52 in plasma of patients with cll and could be used as a tumor marker. although the biological function of cd52 is unknown but it seems that cd52 may be involved in migration and activation of t-cells...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background : previous reports have suggested acute phase proteins, such as albumin, to alter in hemodialysis (hd) patients. intravenous l-carnitine supplementation is expected to improve the level of plasma albumin in hd patients. this study was performed to evaluate the effects of oral l-carnitine supplementation on hemog...

background: various prokaryotic and eukaryotic expression systems have been developed for the production of recombinant proteins. in the present study, we used a new protein expression system based on the iranian lizard leishmania, a trypanosomatid protozoan as a host, for the expression of lpg3 gene from leishmania infantum (l.infantum). methods: the lpg3 gene was cloned in the expression cass...

background: the optimization of bioprocess conditions towards improved growth profile and productivity yield is considered of great importance in biopharmaceutical manufacturing. peptones as efficient sources of nutrients have been studied for their effect on media development however, their role on metabolic pathway is not well understood. methods: in the present study, the effect of different...

background: heat shock proteins (hsp) are highly conserved molecules with many immunological functions. they are highly immunogenic with important role in cancer immunotherapy and in vaccine development against infectious diseases. as adjuvant, hsp can augment the immunogenicity of weak antigens and can stimulate antigen presenting cells. although vaccines have been successful for many infectio...

introduction: tobacco smoke is involved in the pathogenesis of several diseases in different body systems. saliva is the first body fluid that confront inhaled cigarette smoke which is injurious to the oral cavity and is associated with several oral diseases and cancer. the aim of our study was to evaluate the influence of smoking on the activity of alpha-amylase in the saliva of healthy smoker...