Certain bivalent cations, particularly Mg(++) and Mn(++), can be absorbed by yeast cells, provided that glucose is available, and that phosphate is also absorbed. The cation absorption is stimulated by potassium in low concentrations, but inhibited by higher concentrations. From the time course studies, it is apparent that the absorption rather than the presence of phosphate and the potassium i...

Fourteen apparently healthy patients with ileostomies were found to be depleted of total exchangeable sodium and potassium, but had normal serum electrolyte concentrations and normal extracellular fluid and total body water volumes. The low exchangeable sodium and potassiums were thus primarily due to depletion of the intracellular compartment. There was no evidence of renal or intestinal conse...

Potassium has long been known to be almost completely confined to the intracellular compartment, and the neutral fat present in muscle has been shown to have a low chloride content (1). It seemed probable, therefore, that the error associated with predictions of total exchangeable electrolyte from total body weight would diminish if the variable of depot fat was eliminated by the use of lean bo...

1. Whole-body elimination rate of 22Na+ was decreased in normotensive or borderline first-degree relatives of hypertensive probands. 2. Whole-body potassium, exchangeable sodium and urine excretion of sodium, potassium and creatinine were similar in relatives and controls. 3. Erythrocyte net influx of 22Na+ was significantly increased in normotensive relatives. 4. Abnormal whole-body and cellul...

The increase in body weight in congestive heart failure is generally attributed to the retention of sodium and water in the extracellular compartment. Important changes also occur in the intra-cellular space, particularly in the metabolism of potassium. The isotope-dilution technic permits more precise determination of the exchangeable potassium content of the body in congestive failure before ...

Despite the valuable research information on body electrolytes and water that is gained from isotope dilution studies, these investigations have not become routine clinical procedure. This is partly due to the fact that normal ranges for exchangeable sodium (NaE), exchangeable potassium (KE), extracellular fluid volume (E.C.F.V.), and total body water (T.B.W.) are wide owing to great individual...

From determinations of radioactivity and potassium content at intervals after the injection of Rb, it was inferred that most organs of the dog contained exchangeable rubidium in a concentration paralleling but exceeding that of potassium, as compared with their relative concentrations in the plasma. A "lag phenomenon" resulting in higher rubidium specific activity in the myocardium than plasma ...