نتایج جستجو برای: events per variable
تعداد نتایج: 972360 فیلتر نتایج به سال:
We have evaluated the reporting of withdrawals due to adverse effects and specific adverse effects in randomised controlled trials of recombinant human GH in adults. A systematic review was carried out of randomised controlled trials of the clinical effectiveness of recombinant human GH in adults with GH deficiency in relation to impact on quality of life. Trials were identified from searching ...
Background: Medical errors are those mistakes committed by healthcare professionals due to wrong execution of a planned healthcare action or execution of a wrong healthcare action plan whether or not it is harmful to the patient. Medical errors may cause patients to suffer and have huge financial costs for the healthcare system. Identifying and measuring medical errors and adverse events are es...
Despite the widespread use of the apnea-hypopnea index in research, its scientific and statistical properties have not been examined thoroughly. The index may be viewed either as a rate (number of events per hour of sleep) or as a ratio of two variables (number of events/number of hours of sleep). When considered as a rate, the apnea-hypopnea index may be modeled as the dependent variable, prov...
Modern modelling techniques are data hungry: a simulation study for predicting dichotomous endpoints
BACKGROUND Modern modelling techniques may potentially provide more accurate predictions of binary outcomes than classical techniques. We aimed to study the predictive performance of different modelling techniques in relation to the effective sample size ("data hungriness"). METHODS We performed simulation studies based on three clinical cohorts: 1282 patients with head and neck cancer (with ...
We conducted an extensive set of empirical analyses to examine the effect of the number of events per variable (EPV) on the relative performance of three different methods for assessing the predictive accuracy of a logistic regression model: apparent performance in the analysis sample, split-sample validation, and optimism correction using bootstrap methods. Using a single dataset of patients h...
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