In vivo proton nuclear magnetic resonance (1H NMR) studies of ethanol in animal and human brains have shown that only a fraction of ethanol in brain is visible by NMR. The goals of these in vitro 1H NMR experiments were to determine: (1) whether the interaction of ethanol with brain membranes in vitro diminishes ethanol visibility; and (2) if a magnetization transfer (MT) effect can be observed...

Ethanol is renewable and safe fuel and it is mainly produced based on microbial fermentation. The present study aims to isolate and identify ethanol producing Zymomonas spp. from natural environments with characterization, optimization and evaluation of their ethanol productivity. Samples were screened for ethanol producing bacteria on RM medium. Ethanol producing isolates were selected for cha...

Severe ethanol stress (>9% ethanol, v/v) as well as glucose deprivation rapidly induces a pronounced repression of overall protein synthesis in budding yeast Saccharomyces cerevisiae. Therefore, transcriptional activation in yeast cells under severe ethanol stress does not always indicate the production of expected protein levels. Messenger RNAs of genes containing heat shock elements can be in...

Ethanol tolerance is one of the important characteristics of ethanol-producing yeast. This study focused on the improvement of ethanol tolerance of Saccharomyces cerevisiae NR1 for enhancing ethanol production by random UV-C mutagenesis. One ethanol-tolerant mutant, UVNR56, displayed a significantly improved ethanol tolerance in the presence of 15% (v/v) ethanol and showed a considerably higher...

BACKGROUND We previously identified a group of glucocorticoid-responsive genes, including Serum Glucocorticoid kinase 1 (Sgk1), regulated by acute ethanol in prefrontal cortex of DBA2/J mice. Acute ethanol activates the hypothalamic pituitary adrenal axis (HPA) causing release of glucocorticoids. Chronic ethanol dysregulates the HPA response in both humans and rodents, possibly contributing to ...

AIMS The cannabinoid CB1 receptor antagonist, SR141716A, differentially affects the ethanol preference of chronically alcoholized rats when administered during cycles of ethanol exposure and withdrawal. In this study, ethanol preference was investigated in chronically alcoholized rats that underwent regular withdrawal periods during which the brain cannabinoid CB(1) receptor antagonist, SR14171...

Ethanologenic Thermoanaerobacter species produce ethanol from lignocellulose derived substrates at temperatures above 70 degrees C. In the final steps of ethanol formation, two bifunctional acetaldehyde/alcohol dehydrogenases, AdhB and AdhE, and an alcohol dehydrogenase, AdhA, catalyze redox reactions between acetyl-CoA and ethanol via an acetaldehyde intermediate. DNA cloning and analysis reve...

objective: this study was to evaluate the effect of vitamin c on the histology and histochemistry of the prefrontal cortex of ethanol-induced rats. methods: male sprague-dawley rats were used for the study. ethical approval was obtained from the university’s ethical committee. the rats were randomly divided into 6 groups of 10 rats each. rats in group a= free access to normal saline. rats in gr...

background: in this study, the protective effect of thymoquinone (tq) and nigella sativa seeds oil (nso) was evaluated against oxidative damages induced by ethanol in rats. methods: animals were treated with ethanol 40% daily by gavages once a day for 4 weeks. nso and tq were injected intraperitoneal once a day for 4 weeks. the histopathological examination of liver, kidney, brain and heart was...

conclusions the composition of unrecorded samples did not raise major toxicological concern beyond ethanol in alcohol products. however, concentration levels of methanol in some unrecorded alcohol samples made these samples detrimental for human consumption. results of 877 reports of alcohol samples, more than 50% were obtained from mashhad and the rest were from the suburbs. of the reports, 57...