نتایج جستجو برای: estrogen response element
تعداد نتایج: 1193709 فیلتر نتایج به سال:
We report that in endothelial cells, the angiogenic effect of 17beta-estradiol (E2) is inhibited by the estrogen receptor (ER) antagonist ICI or the NO synthase (NOS) inhibitor 7-nitroindazole via downregulation of hTERT, the telomerase catalytic subunit, suggesting that E2 and NO are involved in controlling hTERT transcription. Quantitative Real-Time PCR and chromatin immunoprecipitations in E...
Elevated plasma levels of the lipoprotein particle Lp(a) are a major risk factor for cardiovascular disease. Lp(a) plasma levels are determined by the level of expression of its characteristic protein component, apo(a). Apo(a) expression is modulated by several hormones, of which estrogens are the best known. The chromosomal region responsible for estrogen response was identified within an apo(...
Coordinate, Dominant-Negative Control of Estradiol-Directed Gene Transactivation by an Intracellular Estrogen Binding Protein (Heat shock protein 27; Hsp27) and an Estrogen Response Element Binding Protein (hnRNPC-like Protein) John S. Adams1, Hong S. Chen2, Martin S. Hewison2 1Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA; 2Burns and Allen Research Institute, Ce...
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