background: papillary thyroid carcinoma (ptc), occurs mostly in women and sex hormones may play a role in the pathogenesis and clinical course. the objective of this study was to determine the status and prevalence of estrogen and progesterone receptors in ptc with regard to age, gender, tumor size and lymph node involvement. methods: immunohistochemical stains were performed on 92 tissue block...

background and objective: male breast carcinoma (mbc) is an unusual form of neoplasia, representing 0.7 to 1 percent of all breast cancer cases. usually, the carcinoma affects patients after the sixth decade. the aim of this study was to evaluate the status of estrogen and progesterone receptors (er and pr) and prognostic factors (p53 and her-2/neu) in a series of male patients with breast canc...

We simulate the dynamic and temperature depen dent behavior of two di erent Micro Electro Mechanical Systems MEMS by utilizing recently developed par allel codes which enable a coupling of length scales The novel techniques used in this simulation accurately model the behavior of the mechanical components of MEMS down to the atomic scale by combining the power of an atomistic simulation with th...

SUMMARY: Mesenchymal stem cells (MSCs) and their stromal progeny may be considered powerful regulatory cells, a sort of dendritic cell counterpart, which influence all the main immune effectors and functional roles in vivo, as well as potential applications in the treatment of a number of human immunological diseases. By choosing MSC tissue origin, cell dose, administration route, and treatment...

Breast cancer is the most prevalent neoplasm and second leading cause of death among females in Kenya. Estrogen its metabolites are known risk factors for breast cancer. Polymorphisms these genes susceptibility unique different populations. This study aimed to determine probable associations between estrogen-metabolizing gene variations other Kenyan women. Buffy coat samples were obtained from ...

schizophrenia is a debilitating and pervasive mental illness with devastating effects on many aspects of psychological, cognitive and social wellbeing. epidemiological and life-cycle data point to significant differences in the incidence and course of schizophrenia between men and women, suggesting that estrogen plays a “protective” role . adjunctive estrogen therapy has been shown to be effect...

Breast cancer death polls are rising at an alarming rate in females globally. It is a hormone-dependent disease that majorly regulated by estrogen. Several genetic and environmental factors the primary attributes of breast growth development. A higher proportion patients harbor estrogen receptor-positive (ER+ve) status. Estrogen related receptors orphan nuclear which include ERRα, ERRβ, ERRϒ ex...

introduction: the etiology of male breast cancer is unclear, but hormonal levels may play a role in development of this disease. it seems that the risk of male breast cancer related to increased lifelong exposure to estrogen or reduced androgen. the aim of this study was to investigate the expression of the steroid hormone receptors including estrogen receptor (er) and progesterone receptor (pr...

Background and Objective: Breast cancer is the commonest cancer of Indian women. Estrogen and Progesterone expression is seen in benign breast lesions and in breast carcinoma associated with good prognostic parameters and it correlates well with response to hormone therapy. Although a lot of studies have been conducted in the past on hormone receptor expression in breast cancer and few have cor...