Achalasia is a primary esophageal motility disorder that involves failure of the lower sphincter to relax in response swallowing. Specifically, becomes hypertensive, and there an absence peristalsis esophagus. The pathophysiology thought be due loss inhibitory nerve function from autoimmune attack targets myenteric nerves. As result, these abnormalities lead functional obstruction at gastroesop...

leiomyoma of the esophagus is rare, but it is the commonest among the benigh tumors of the esophagus. among 95 cases of esophageal tumors, there was just 4 cases of leiomyoma (3 were females and 1 was male) and this is contrary to the reports already published. main symptoms of esophageal leiomyoma include: disphagia, pain and hematemesis from the above mentioned cases 1 tumor was in the thorac...

OBJECTIVE The pathophysiological data on Barrett's esophagus are scant in Asia, so the purpose of this study was to compare and analyze the pathophysiological characteristics of Barrett's esophagus and reflux esophagitis among Chinese in Taiwan. PATIENTS AND METHODS From November 2001 to January 2003, fifteen patients with Barrett's esophagus were consecutively enrolled as the Barrett's esoph...

BACKGROUND The CDX2 (caudal-related homeobox gene 2) and PITX1 (pituitary homeobox 1) genes have essential roles in human development. Forced expression of Cdx2 alone in the murine stomach results in gastric intestinal metaplasia (IM). This study was undertaken to investigate the expression pattern of these critical morphogenesis genes in the Barrett's multistage carcinogenesis model. METHODS...

Histological development of digestive tract of the Caspian salmon, Salmo trutta caspius, from hatching to 6 month post-hatching was studied using light microscope. The digestive tract of newly hatched larvae was a simple, undifferentiated tube which continued from mouth to anus. In 10 days post hatching larvae, the alimentary canal became more differentiated and secretion was started activity, ...

BACKGROUND Once-in-a-lifetime screening for Barrett esophagus has been proposed for patients with gastroesophageal reflux disease (GERD), but there is little evidence of its cost-effectiveness. OBJECTIVE 1) To determine the cost-effectiveness of screening high-risk groups for Barrett esophagus and providing surveillance to patients with Barrett esophagus and dysplasia or to all patients with ...

The anatomy of the esophagus was previously studied in most mammals. The esophagus was composed of three parts in the cat as typical anatomical animals: cervical, thoracic, and abdominal [1-3]. While in canine the esophagus was consisted of the upper esophageal sphincter, the tubular esophagus, and the lower esophageal sphincter [4]. In canine the first part of esophagus lies dorsal to the trac...

Heterotopic gastric mucosa (HGM) of the esophagus is a congenital anomaly consisting of ectopic gastric mucosa. It may be connected with disorders of the upper gastrointestinal tract, exacerbated by Helicobacter pylori. The diagnosis of HGM is confirmed via endoscopy with biopsy. Histopathology provides the definitive diagnosis by demonstrating gastric mucosa adjacent to normal esophageal mucos...