Endocytic trafficking is a critical mechanism for cells to decode complex signaling pathways, including those activated by G-protein-coupled receptors (GPCRs). Heterogeneity in the endosomal network enables GPCR activity to be spatially restricted between early endosomes (EEs) and the recently discovered endosomal compartment, the very early endosome (VEE). However, the molecular machinery driv...

Venezuelan equine encephalitis virus (VEEV) is an emerging pathogen of equids and humans, but infection of its rodent reservoir hosts has received little study. To determine whether responses to infection vary among geographic populations, we inoculated 3 populations of cotton rats with 2 enzootic VEEV strains (Co97-0054 [enzootic ID subtype] and 68U201 [enzootic IE subtype]). The 3 populations...

We consider classical solutions of the inviscid Surface Quasi-geostrophic equation that are a small perturbation $\epsilon$ from radial stationary solution $\theta=|x|$. use modified energy method to prove existence time $\frac{1}{\epsilon}$ scale $\frac{1}{\epsilon^4}$. Moreover, by perturbing in suitable direction we construct global smooth solutions, via bifurcation, rotate uniformly and spa...

Our aim in this paper is to introduce and study a new sort of fuzzy ternary subsemigroup (left ideal, right ideal, lateral ideal, quasi-ideal, bi-ideal) of a ternary semigroup, called interval-valued (α,β )-fuzzy ternary subsemigroup (left ideal, right ideal, lateral ideal, quasi-ideal, bi-ideal). We also characterize regular ternary semigroups in terms of these interval-valued fuzzy ideals.

Venezuelan equine encephalitis (VEE) is reemerging in Peru. VEE virus subtype ID in Peru has not been previously associated with severe disease manifestations. In 2006, VEE virus subtype ID was isolated from a boy with severe febrile disease and gastrointestinal bleeding; the strain contained 2 mutations within the PE2 region.

One of the most important questions in arbovirology concerns the origin of epidemic Venezuelan equine encephalitis (VEE) viruses; these viruses caused periodic, extensive epidemics/epizootics in the Americas from 1938-1973 (reaching the United States in 1971) but had recently been presumed extinct. We have documented the 1992 emergence of a new epidemic/epizootic VEE virus in Venezuela. Phyloge...

An epitope-blocking enzyme-linked immunosorbent assay was developed for the rapid differentiation of serologic responses to enzootic variety IE and ID versus epizootic variety IAB and IC strains of Venezuelan equine encephalitis (VEE) virus. Two monoclonal antibodies that differentially recognize epizootic versus enzootic VEE virus epitopes were used to measure the serotype-specific blocking ab...

in this paper, we introduce the concept of the   generalized aip-rings as a generalization of the generalized quasi-   baer rings   and generalized p.p.-rings. we show that the class of the generalized aip-rings is closed under direct products and morita invariance. we also characterize the 2-by-2 formal upper triangular matrix rings of this new class of rings. finally, we provide sever...

Effective and reliable assessment approaches to computational thinking in secondary education are demand. This paper uses a guided technological pedagogical content knowledge (TPACK) framework, incorporating visual execution environment (VEE) Scratch project for school students as method teach assess thinking. The objective is investigate if programming concepts can be improved upon following t...

The Finagle point (Wuffle et al., 1989), the yolk (McKelvey, 1986; Ferejohn et al., 1984) and the epsilon-core (Wooders, 1983; Salant and Goodstein, 1990; Tovey, 2010; Feld and Grofman, 1991) are three solution concepts that have been proposed to predict the outcome of majority voting in the Euclidean spatial model. Relationships among these three concepts are investigated in (Bra̋uninger, 2007)...