..................................................................................................... 3 List of publications .................................................................................... 4 List of abbreviations .................................................................................. 6 Introduction ....................................................................

X- and Q-band electron paramagnetic resonance (EPR) spectroscopy was used to characterize polycrystalline Cu(II) complexes that contained sodium 5-sulfonate salicylaldehyde thiosemicarbazones possessing a hydrogen, methyl, ethyl, or phenyl substituent at the terminal nitrogen. The ability of thiosemicarbazone proligands to generate superoxide radical anions and hydroxyl radicals upon their expo...

............................................................................................. Introduction.......................................................................................... I. Literature overview 1. DNA G-quadruplexes........................................................................... 1.1 Structural characterization....................................................

Particulate methane monooxygenase (pMMO) catalyzes the oxidation of methane to methanol in methanotrophic bacteria. As a copper-containing enzyme, pMMO has been investigated extensively by electron paramagnetic resonance (EPR) spectroscopy, but the presence of multiple copper centers has precluded correlation of EPR signals with the crystallographically identified monocopper and dicopper center...

A combination of molecular mechanics (MM), electron paramagnetic resonance spectroscopy (EPR), and spectra simulation (MM-EPR) has been used to determine the solution structures of di- and trinuclear copper(II) complexes of melamine-based oligomacrocyclic ligands. The spin Hamiltonian parameters of the mononuclear, melamine-appended macrocyclic ligand copper(II) complex have been determined by ...

Three five-coordinate, high spin manganese(ii) "picket fence" porphyrin complexes, [Mn(TpivPP)(L)] (TpivPP = α,α,α,α-tetrakis(o-pivalamidophenyl)porphyrinato; L = 1-MeIm (1-methylimidazole), 1-EtIm (1-ethylimidazole) and 2-MeHIm (2-methylimidazole)), are synthesized and studied by single-crystal X-ray, UV-vis and electronic paramagnetic resonance (EPR) spectroscopy. Structural parameters are in...

A set of four copper(ii) complexes, and (X = Cl, Br; = N-(l-leucine methyl ester)-N'-((2-pyridin-2-yl)methyl)oxalamide and = N-benzyl-N'-((2-pyridin-2-yl)methyl)oxalamide), have been synthesized and characterized by X-ray structural analysis, electron paramagnetic resonance (EPR) spectroscopy on single crystals and by SQUID magnetization measurements. X-ray diffraction studies show one-dimensio...

Electron paramagnetic resonance spectroscopy and density functional theory methods were used to study the structure of a single, high-affinity Mn(II) binding site in the hammerhead ribozyme. This binding site exhibits a dissociation constant Ke of 4.4 microM in buffer solutions containing 1 M NaCl, as shown by titrations monitored by continuous wave (cw) EPR. A combination of electron spin echo...

Oxalate decarboxylase (OxDC) catalyzes the Mn-dependent conversion of the oxalate monoanion into CO2 and formate. EPR-based strategies for investigating the catalytic mechanism of decarboxylation are complicated by the difficulty of assigning the signals associated with the two Mn(II) centers located in the N- and C-terminal cupin domains of the enzyme. We now report a mutational strategy that ...