INDEPENDENT EPILEPTIFORM DISCHARGE PATTERNS IN THE OLFACTORY AND LIMBIC AREAS OF THE IN 2 VITRO ISOLATED GUINEA PIG BRAIN DURING 4-AMINOPYRIDINE TREATMENT 3 4 Giovanni Carriero, Laura Uva, Vadym Gnatkovsky, Massimo Avoli and Marco de 5 Curtis 6 7 Unit of Experimental Neurophysiology and Epileptology, Fondazione Istituto Neurologico C. 8 Besta, via Celoria 11, 20133 Milano, Italy; Montreal Neuro...

ObjectiveAlthough epileptic seizures occur in approximately a quarter of patients with Aicardi-Goutières syndrome (AGS), their phenotypic and electrophysiological characterization remains elusive. The aim our study was to characterize epilepsy phenotypes electroencephalographic (EEG) patterns AGS look for possible correlations clinical, genetic neuroradiological features.MethodsWe selected an e...

The idea of the epileptic brain being highly excitable and facilitated to synchronic activity has guided pharmacological treatment since early twentieth century. Although tackling epilepsy's seizure-prone feature, by tonically modifying overall circuit excitability and/or connectivity, last 50 years drug development not seen a substantial improvement in seizure suppression refractory epilepsies...

Members of the working group: Svetlana B. Artemyeva, MD, PhD, Head Neurological department Research Clinical Institute Pediatrics named after Yu.E. Veltishchev; Russian Federation; Elena D. Belousova, DSci, Professor, Department psychoneurology and epileptology pediatrics, Veltishchev, Dmitry V. Vlodavets, President Association Pediatric Neurologists in field myology NeoMyo, Children’s Neuromus...

This volume is the latest in a series of texts on different aspects of paediatric epilepsy produced by the Mariani Foundation in Italy and published by John Libbey & Co. Previous volumes have been well received within the epileptology community and in seeking to address the question of limbic disease in children the editors have sought to address an important area of childhood epileptology and ...

a Potsdam Institute for Climate Impact Research, Telegraphenberg A 31, 14473 Potsdam, Germany b Max-Planck-Institute for the Physics of Complex Systems, Nöthnitzer Straße 38, 01187 Dresden, Germany c Department of Physics, Humboldt University Berlin, 12489 Berlin, Germany d Institute for Complex Systems and Mathematical Biology, University of Aberdeen, Aberdeen AB24 3UE, United Kingdom e Depart...

Consciousness is a central concept in epileptology, relevant to the understanding of both focal and generalized seizures. Within focal seizures, impairment of consciousness has long been considered as the main criterion differentiating complex partial seizures (CPS) from simple partial seizures With the development of improved tools for investigating human brain function, new insights into the ...

CTRS-IDEE, Hospices Civils de Lyon, INSERM U821, University Claude Bernard Lyon 1 and Neuroscience Federative Institute of Lyon, Lyon, Department of Functional Neurology and Epileptology, Hospices Civils de Lyon, INSERMU879, University Claude Bernard Lyon 1 and Neuroscience Federative Institute of Lyon, Lyon, France, Department of Clinical Neuroscience, Division of Neuroscience and Mental Healt...