نتایج جستجو برای: epc or turnkey projects

تعداد نتایج: 3608395  

Journal: :Circulation research 2007
Thomas Thum Sarah Hoeber Sabrina Froese Ivonne Klink Dirk O Stichtenoth Paolo Galuppo Marten Jakob Dimitrios Tsikas Stefan D Anker Philip A Poole-Wilson Jürgen Borlak Georg Ertl Johann Bauersachs

Aging is associated with an increased risk for atherosclerosis. A possible cause is low numbers and dysfunction of endothelial progenitor cells (EPC) which insufficiently repair damaged vascular walls. We hypothesized that decreased levels of insulin-like growth factor-1 (IGF-1) during age contribute to dysfunctional EPC. We measured the effect of growth hormone (GH), which increases endogenous...

2015
Joan Martí-Fàbregas Raquel Delgado-Mederos Javier Crespo Esther Peña Rebeca Marín Elena Jiménez-Xarrié Ana Fernández-Arcos Jesús Pérez-Pérez Alejandro Martínez-Domeño Pol Camps-Renom Luís Prats-Sánchez Francesca Casoni Lina Badimon

BACKGROUND AND PURPOSE We evaluated the hypothesis that the number of circulating EPC could be associated with the risk of stroke recurrence (SR) or vascular events (VE) after an ischemic stroke. METHODS We studied prospectively consecutive patients with cerebral infarction within the first 48 hours after the onset. We recorded demographic factors, vascular risk factors, previous Rankin scale...

2011
Nobuhisa Nakamura Keiko Naruse Yasuko Kobayashi Takashi Matsuki Yoji Hamada Eitaro Nakashima Hideki Kamiya Masaki Hata Toru Nishikawa Atsushi Enomoto Masahide Takahashi Toyoaki Murohara Tatsuaki Matsubara Yutaka Oiso Jiro Nakamura

UNLABELLED Aims/Introduction:  Endothelial progenitor cells (EPC) play a critical role in adult vasculogenesis and vascular repair. Previous studies have described the dysfunction of EPC in diabetic patients, but the precise mechanism is still unclear. To elucidate the dysfunction of EPC in diabetic patients, we investigated the functions and intracellular signaling of EPC under normal or high ...

2012
R. Tavakkoli-Moghaddam S. M. Mousavi H. Hashemi

Long lasting complicated processes and organizational features generate abundant risks in Engineering, Procurement and Construction (EPC) projects. Iran witnesses an unprecedented boom in engineering, procurement and construction activities at all levels with the government’s goal of diversifying its income away from oil dependence to commercial and industrial activities based on the fourth eco...

Journal: :Haematologica 2007
Cátia Igreja Margarida Courinha Ana Sofia Cachaço Teresa Pereira José Cabeçadas Maria Gomes da Silva Sérgio Dias

BACKGROUND AND OBJECTIVES Endothelial progenitor cells (EPC) have been proven to be essential for tumor angiogenesis and growth in animal tumor models. However, the involvement and relevance of EPC in human cancers remain poorly studied. We, therefore, investigated the presence, differentiation potential and molecular characteristics of EPC in lymphoma patients. DESIGN AND METHODS EPC (CD133+...

Journal: :International Journal of Engineering and Management Research 2018

Journal: :PLoS ONE 2007
Qingzhong Xiao Stefan Kiechl Seema Patel Friedrich Oberhollenzer Siegfried Weger Agnes Mayr Bernhard Metzler Markus Reindl Yanhua Hu Johann Willeit Qingbo Xu

BACKGROUND EPC number and functionality are assumed to reflect the endogenous vascular repair capacity with the EPC pool declining in higher ages and being exhausted by unfavorable life-style and risk factors. This intriguing and clinically highly relevant concept, however, has so far been derived from small case-control studies and patient series. METHODOLOGY AND PRINCIPLE FINDINGS In the po...

Journal: :Circulation research 2005
Dirk H Walter Judith Haendeler Johannes Reinhold Ulrich Rochwalsky Florian Seeger Jörg Honold Jörg Hoffmann Carmen Urbich Ralf Lehmann Fernando Arenzana-Seisdesdos Alexandra Aicher Christopher Heeschen Stephan Fichtlscherer Andreas M Zeiher Stefanie Dimmeler

Transplantation of bone marrow cells as well as circulating endothelial progenitor cells (EPC) enhances neovascularization after ischemia. The chemokine receptor CXCR4 is essential for migration and homing of hematopoietic stem cells. Therefore, we investigated the role of CXCR4 and its downstream signaling cascade for the angiogenic capacity of cultured human EPC. Ex vivo, differentiated EPC d...

2011
Kim E Jie Karien van der Putten Marloes W T Bergevoet Pieter A Doevendans Carlo A J M Gaillard Branko Braam Marianne C Verhaar

OBJECTIVE Patients with cardiorenal syndrome (CRS) have high cardiovascular morbidity. Endothelial progenitor cells (EPC) constitute an endogenous vascular repairsystem, protecting against atherosclerosis development. Erythropoietin (EPO) treatment may have beneficial effects by mobilizing EPC from the bonemarrow. Our objective is to determine EPC levels and effects of EPO therapy on EPC levels...

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The purpose of this study was to determine the effect of two different intensities of physical activity on circulating endothelial progenitor cells (EPC) in healthy young women. For this purpose, 15 female students from volunteers were randomly selected via questionnaire (group 1: mean age 22 ±1/8 years, BMI 20/81±1/91 kg/m2, n = 8. group 2: mean age 21 ±1/5 years, BMI 20/38 ± 1/66 kg/m2, ...

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